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What is the malt lymphoma disease?
MALT lymphoma is a form of lymphoma involving the lymphoid tissue, frequently of the stomach. MALT lymphoma is a cancer of the B-cell lymphocytes. It usually affects older people who are in their 60s.
What medical periodical is available on gastric MALT lymphoma?
Zucca, E., et al. "The Gastric Marginal Zone Lymphoma of MALT Type." Blood 96 (July 2000): 410-19.
How is suspicion of MALT lymphoma confirmed?
It is unusual for masses recognizable as tumors to be seen upon examination. Definitive diagnosis of MALT lymphoma requires a biopsy, in which a bit of tissue is removed from the stomach or other involved site.
What causes treatment for some MALT lymphoma patients to be ineffective?
It may be the case that in these patients, the MALT lymphoma may have already progressed to a point where high-grade lesions, not observed in the original biopsies, were resistant to the initial treatment.
What does being diagnosed with malt lymphoma mean?
This is a type of cancer that isn't produced in the nodes but through other organs. Most patients diagnosed with malt lymphoma find that this cancer is generally diagnosed before it spreads to a larger area of the body.
What serious disease may develop in those with MALT lymphoma?
Individuals who develop MALT lymphomas are more likely to develop other forms of cancer.
What is the typical prognosis for MALT lymphoma?
In general, the prognosis for patients with MALT lymphomas is good, with overall five-year survival rates that are greater than 80%.
Patient with MALT lymphoma who do not respond to standard treatment undergo what alternative therapy?
In general, these patients are treated with chemotherapy in a similar manner to patients with other types of lymphoma.
What clinical trials are being conducted on MALT lymphoma?
Clinical trials are underway and mostly concentrate upon optimizing treatment of gastric MALT lymphomas that involve H. pylori.
When are early diagnoses of MALT lymphoma usually made?
The indolent nature of most MALT lymphomas means that the majority of patients are diagnosed at early stages with relatively nonspecific symptoms.
What specialist is needed to distinguish MALT lymphoma from other conditions?
Examination of this tissue by a pathologist is the first step in distinguishing among the possible diagnoses of inflammation, indolent lymphoma, or a more aggressive form of cancer
What has been the stumbling block in determining the optimal treatment for MALT lymphoma?
While the outlook for patients with MALT lymphomas is good, difficulties in diagnosis and staging have left the optimal treatment a matter of continued study.
