Is cramping normal in the first trimester?

Yes, my wife had random cramping the entire pregnancy. Cramping during pregnancy, unfortunately, can mean multiple things; some are okay and some are not so good. It can be gas, constipation, your uterus growing; signs of an ectopic pregnancy, miscarriage, and the list can go on and on. If the cramping continues and it concerns you too much you should contact your doctor.