No. It works by blocking the Chloride channels in nerve cells, causing over-excitation. Has a much higher affinity for insect than mammal Cl channels
Organophosphate pesticides attack the nervous system of insects and animals leading to death. These are dangerous.
Curare is a good antidote for organophosphate poisoning because it acts as a competitive antagonist at the neuromuscular junction, blocking the effects of excessive acetylcholine caused by organophosphate inhibition of acetylcholinesterase. This helps to alleviate muscle paralysis and respiratory distress associated with organophosphate toxicity. However, curare does not reverse the underlying toxic effects on the central nervous system, so it is often used in conjunction with other treatments like atropine and pralidoxime for comprehensive management.
Why does oranophosphate poisoning cause muscular paralysis? Why does oranophosphate poisoning cause muscular paralysis?
Both military nerve gases and organophosphate insecticides are nerve agents. It is highly unlikely you will be exposed to military nerve gases, unless you were near the front lines during a war in which they were used or you were trying to help treat wounded soldiers that had been exposed to them. Every time you use an organophosphate insecticide to kill pests you expose yourself too.
Organophosphates are a wide range of products that act on an insects central nervous system. The vast majority of residual insecticides are organos.
R. Derache has written: 'Organophosphorus pesticides' -- subject(s): Organophosphate Insecticides, Organophosphorus compounds, Pesticides, Toxicology
Organophosphate
Anything classified as an organophosphate. No one can list them all, but these effect an insect's nervous system. Orthene, anything containing pyrethrins, for example.
Atropine is combined with pralidoxime chloride to counteract organophosphate poisoning (used in some but not all modern nerve agents as well as insectocides).
I don't know how detailed an answer you want, but here's the overview:Organophosphates irreversibly bind to the enzyme acetycholinesterase. Acetylcholinesterase is responsible for breaking down acetylcholine in the body. Acetylcholine is part of the mechanism that causes muscle contractions. At normal bodily levels, this allows us to move, breathe, and digest food. However, if the enzyme that breaks it down (acetylcholinesterase) is chemically bound to something else (organophosphates) then acetylcholine builds up in the body. This can cause muscle spasms, nausea (if it affects the gastrointestinal tract), seizures, difficulty breathing (if it affects the muscles that control expansion and contraction of the lungs), among other things. If exposure levels are high enough, organophosphate poisoning will cause death. I know that some treatments for organophosphate poisoning exist, but I do not know what they are, or how effective they are.The body will continue to produce acetylcholinesterase, but if there are still unbound organophosphate molecules, they will take up this amount of enzyme as well, thus continuing the toxic effects even after exposure has been stopped.I hope this answered your question.
A pest-killer that contains organic compounds, includes phosphorus and operates neurotoxically describes an organophosphate pesticide. The pesticides in question functioned in nerve gases. They tend to be used nowadays as fire retardants and in insecticides, such as in mosquito abatement schedules in public parks, even though they disrupt messages from the brain to nerve endings and link to behavioral and emotional changes, cancer, cardiovascular and respiratory problems, permanent brain damage and premature births.
No. Organophosphate pesticides kill insects not humans because humans can break them down. But other organophosphate poisons called nerve gases kill both insects and humans. This same effect is true for many other poisons, some organisms can break them down while others can't. Bacteria and some plants are killed by antibiotics that damage cell walls. But animals and fungi are unaffected by antibiotics as their cells lack cell walls.