No it isn't; the two words have entirely different meanings.
The best synonym for vacuous is 'intelligent'
Clever Intelligent
Intelligent
Many people believe that creationism is a one word synonym for intelligent design. Though this is not true, I hope it may be the answer you are looking for.
Analytical, intelligent, pertinent, etc.
no it is not... "ponder" and "wonder", however, are
Smart, intelligent, perceptive
A synonym for "intelligent" is "smart." Other synonyms include "wise," "brilliant," and "clever." These words convey a similar meaning related to the ability to think, understand, and learn effectively.
smart
Perceptive, intelligent, clever, savvy, perspicacious, canny, sharp...
Genius Intellectual Smart Academic brilliant brainy intelligent
A synonym for the word "inane" is idiotic. An antonym for "inane" is intelligent. Please see the related link below.