Insanitity
With knives.
He sends murderers to do it.
When the murderers kill Banquo, Fleance (Banquo's son) flees. And the murderers only kill Banquo not Fleance however Macbeth told the murderers to kill both the father and the son.
Yes, it does happen.
Enough to kill you.
Macbeth sets an ambush for Banquo with three murderers. The murderers kill Banquo but Banquo's son Fleance escapes.
The murderers fail to kill Fleance.
Macbeth instructed the murderers to kill Banquo and his son Fleance.
Through the apparitions of three witches, Macbeth hires murderers. The murderers whom Macbeth hires to kill the father-and-son team of Banquo and Fleance remain nameless. We don't know whether they're the same murderers who subsequently kill the family and wife of Macduff, thane of Fife.
Banquo is on his way to a royal banquet when he is attacked by the murderers sent by Macbeth. The murderers ambush him and kill him, but his son Fleance manages to escape.
Macbeth sends murderers to kill Macduff's family in an attempt to eliminate any potential threats to his own power. This ruthless act solidifies Macbeth's descent into tyranny and cruelty, as he seeks to maintain his position on the throne at any cost. The murder of Macduff's family ultimately leads to Macduff seeking revenge against Macbeth, contributing to his downfall.