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Excedrin PM contains acetaminophen (Tylenol) and diphenhydramine (Benadryl).

It can be taken nightly with minimal risk, however, if you feel the need to take something for pain and sleep every night, you should speak with your doctor.

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13y ago
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13y ago

Yes and no. If you are in pain and can't sleep as a result, go for the recommended dose. If you just can't sleep, spare your liver and get generic diphenhydramine (benedryl), as this is the ingredient that makes you fall asleep. It is safe for long term use on its own, but getting to the root of your sleeplessness is important.

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