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When was paclitaxel discovered?
Paclitaxel was discovered in 1967 by researchers at the Research Triangle Institute in North Carolina.
How much bark is needed to make 120 kilograms of paclitaxel?
Approximately 3,000 kilograms of bark is needed to make 120 kilograms of paclitaxel, as the yield of paclitaxel from the bark of the Pacific yew tree is around 0.04-0.05%.
Paclitaxel is the drug of which company?
Paclitaxel is a generic name used by generic pharmaceutical producers, such as the Israeli company Teva. It is extracted from Yew tree bark and purified through various solvent extraction / crystallisation steps. Paclitaxel is a natural product with antitumor activity. It is sold under the registered tradename TAXOL® by the Bristol Myers-Squibb company as a semi-synthetic chemotherapy drug, processed from Taxus baccata (Yew). See http://www.bms.com/products/data/index.html
Lymphoma is cancer of the lymph node tissue that's sometimes treated with what lotion?
diethylstilbestrol mechlorethamine paclitaxel carboplatin
What has the author Tracy Lynn Burton written?
Tracy Lynn Burton has written: 'Localization of paclitaxel in Taxus cuspidata'
Lymphoma is cancer of the lymph node tissue that's sometimes treated with lotion.?
diethylstilbestrol mechlorethamine paclitaxel carboplatin
Which checkpoint in the cell cycle is affected by paclitaxel?
Paclitaxel primarily affects the mitotic checkpoint in the cell cycle. It stabilizes microtubules and prevents their depolymerization, disrupting proper spindle formation and leading to mitotic arrest. This interference ultimately triggers cell cycle checkpoints that can result in apoptosis if cells cannot successfully complete mitosis.
What is the chemical in yew tree bark?
The chemical in yew tree bark is taxol, which is a powerful anti-cancer compound that has been used in cancer treatments.
What does natural taxol come from?
Taxol, also known as paclitaxel, is a chemotherapy medication derived from the Pacific yew tree (Taxus brevifolia). It is extracted from the bark of the tree.
What was the original source of the chemotherapy drug Taxol paclitaxel?
The chemotherapy drug Taxol, or paclitaxel, was originally derived from the bark of the Pacific yew tree (Taxus brevifolia). Discovered in the 1960s, it was found to have significant anti-cancer properties, particularly effective against ovarian and breast cancers. The extraction process from the yew tree was initially complex and unsustainable, leading to the development of semi-synthetic methods for production.
What has the author Jamei R Eng written?
Jamei R. Eng has written: 'Pharmacogenomics of paclitaxel and doxorubicin resistance in human MCF-7 breast cancer cell lines'
Is it safe to take zopiclone and paclitaxel and carboplatin chemotherapy?
Zopiclone is a sedative used for short-term treatment of insomnia, while paclitaxel and carboplatin are chemotherapy agents used to treat various cancers. While there are no direct contraindications between zopiclone and these chemotherapy drugs, it's essential to consult your healthcare provider before combining them. They can assess your specific health situation and potential interactions, ensuring your safety during treatment. Always follow medical advice tailored to your individual needs.
