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A combination of genetic and environmental factors play a role in the development of schizophrenia.[2][3] People with a family history of schizophrenia who suffer a transient psychosis have a 20-40% chance of being diagnosed one year later.[23]
Estimates of heritability vary because of the difficulty in separating the effects of genetics and the environment.[24] The greatest risk for developing schizophrenia is having a first-degree relative with the disease (risk is 6.5%); more than 40% of monozygotic twins of those with schizophrenia are also affected.[3] It is likely that many genes are involved, each of small effect and unknown transmission and expression.[3] Many possible candidates have been proposed, including specific copy number variations, NOTCH4, and histone protein loci.[25] A number of genome-wide associations such as zinc finger protein 804A have also been linked.[26] There appears to be significant overlap in the genetics of schizophrenia and Bipolar disorder.[27]
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Is schizophrenia a genetic disorder?
Schizophrenia is partly genetic- one out of ten people who have at least one schizophrenic relative also have schizophrenia (compared to one out of one hundred people in general). About one out of two people whose identical twins have schizophrenia also have schizophrenia. However, schizophrenia is not completely genetic. If schizophrenia was completely genetic, everyone who had an identical twin with schizophrenia would also have schizophrenia. This is not the case. Like I said before, about 50% of people whose identical twins have schizophrenia also have schizophrenia. There are environmental as well as genetic factors to schizophrenia.
Can schizophrenia occur in those without a genetic predisposition?
Yes, schizophrenia may occur without a specific genetic predisposition for it.
Is schizophrenia caused by genetic or environmental factors?
Schizophrenia occurs in the mind, genetic and environmental factors can affect it, but do not directly cause it.
Is Schizophrenia a autosomal dominant disorder?
No. Schizophrenia is not completely genetic, and it also has multiple genes that can cause it.
What are suspected causes in schizophrenia and alzheimers?
Genetic abnormalities
Is there a strong genetic predispostion toward schizophrenia?
Yes. Half of the people whose identical twins have schizophrenia also have schizophrenia, implying that there is a strong genetic link. However, environmental causes also play a part.
Can schizophrenia be inherited?
Yes, it can, although it is not completely genetic. People with 1 parent with schizophrenia have a 9% chance of developing schizophrenia, which is 9 times that of the general population. People with two parents with schizophrenia have a 36% chance of developing schizophrenia, which is 36 times that of the general population. This shows that there is a strong genetic link.
Is schizophrenia dominant or recessive?
Schizophrenia is only partially genetic, and therefore is neither recessive nor dominant.
Is schizophrenia autosomal or sex-linked?
The genetic factors affecting the risk of schizophrenia are not yet fully known, but the genes currently associated with schizophrenia are autosomal.
Is schizophrenia autosomal recessive or dominant?
Schizophrenia is only partially genetic, and therefore is neither recessive nor dominant.
If a 30 year old has schizophrenia could the mother have it as well?
Yes. Schizophrenia is partly genetic, meaning that if you have a relative with schizophrenia you are likely to also have schizophrenia. About 1/10 of people with a relative with schizophrenia develop schizophrenia, compared to 1/100 people without a relative with schizophrenia.
Can schizophrenia and depression be inherited?
Yes, they can, although they are not completely genetic. People with 1 parent with schizophrenia have a 9% chance of developing schizophrenia, which is 9 times that of the general population. People with two parents with schizophrenia have a 36% chance of developing schizophrenia, which is 36 times that of the general population. This shows that there is a strong genetic link. There are similar statistics for depression.
