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Yes. It may cause nephrotoxicity (damage to the nephrons of the kidney, which will lead to renal failure, which may eventually cause a need for hemodialysis, or worse, death) if the daily maximum of 3,200 mg ibuprofen is exceeded.

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14y ago
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12y ago

Yes! It most commonly causes gastrointestinal bleeds by corroding your stomach lining. This can happen in both overdose cases as well as people who take it on a regular basis for a number of years. Advil can also be harmful to your liver, eventually causing liver failure. Liver failure is seen more in overdose cases.

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16y ago

It can be. You MUST drink a lot of water or fluids when you take it.

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10y ago

You explode.

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