The 2012 Lexus CT-200H has front wheel drive.
The 2012 Lexus RX-450H has front wheel drive.
The 2012 Lexus RX-350 has front wheel drive.
The 2012 Lexus ES-350 has front wheel drive.
The 2012 Lexus LFA has rear wheel drive.
The 2012 Lexus IS-250 has rear wheel drive.
The 2012 Lexus IS-350 has rear wheel drive.
The 2012 Lexus LS-460 has rear wheel drive.
The 2012 Lexus IS-250-C has rear wheel drive.
The 2012 Lexus IS-350-C has rear wheel drive.
The 2012 Lexus GX-460 has four wheel drive.
The 2012 Lexus LS-600H-L has all wheel drive.