Need to give a specific point in NC... it's a pretty substantially sized state, after all, and the distance from, say, Rocky Mount will be significantly different than it will be from Charlotte, as will the halfway point.
Toledo?
The halfway point between Hanover, MD and Toledo, Ohio falls in or around Indianola, PA.
The halfway point between Pelham Drive, Fort Wayne Indiana, and Toledo, Ohio falls in or around Defiance, Ohio. There is no city of Pelham.
Benezette, Pennsylvania is the halfway point between Long Island, New York and Toledo, Ohio. There is approximately 604 miles between New York and Ohio.
Hotchkiss, VA.
Caledonia, IL
Davidsburg, MI
Somewhere in northern Ohio, not far from Toledo!
Flat Rock, Mi
Dayton Ohio
The halfway point falls around Indiana Toll Road, Howe, IN 46746, USA.
Approximately Toledo, Ohio.