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Assuming the two are both normal, no. A difference in the number of chromosomes is generally associated with severe birth defects. Most such children will not even make it to birth alive. The most common chromosome anomaly in humans is Down syndrome, which is comparatively mild in that it doesn't automatically result in the death of the fetus before or shortly after birth.(I'm assuming you mean "number of chromosomes per cell"; an 18 year old will have more chromosomes in total than an 8 month old simply by virtue of being larger and having more cells.)

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Q: Is there any difference in number of chromosomes when 8 months child is compared with 18 years old persons?
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