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Neither. People with sickle cell anemia have the same number of chromosomes and even the same number of genes as those who don't have the disease. The difference is a *change* in one of the genes. Actually, it is (usually) caused by a one letter difference in the hemoglobin gene which makes the hemoglobin produced more 'sticky' on a molecular level.
What else can I help you with?
What occurs in hemolytic anemia?
so many red cells are destroyed that most of the available haptoglobin is needed to bind the released hemoglobin. The more severe the hemolysis, the less haptoglobin remains in the blood.
When do the symptoms of sickle cell anemia appear?
If you have sickle cell anemia and already know it, then it wil lbe pretty easy to tel lwhen the symptoms show themselves. I don't have it myself but people with sickle cell apparently go through a lot of pain when a sickle cell gets stuck in a blood vessel and causes a clot; there isn't a cure, just doctors can give stuff to make the pain less but not totally go awayunless maybe they knock you unconscious. Also people with sickle cell have more trouble with sports and activites since sickle cells can't carry as much oxygen as normal ones. I'm sorry, but that's all the symptoms I know...
Can you join the military with sickel cell disease?
AR 40-501 Chapter 2 Physical Standards for Enlistment, Appointment, and Induction 2-4. Blood and blood-forming tissue diseases a. Anemia. Current hereditary or acquired anemia, which has not been corrected with therapy before appointment or induction, is disqualifying. For the purposes of this regulation, anemia is defined as hemoglobin of less than 13.5 for males and less than 12 for females. The following ICD-9 codes are used for diagnosed anemia: hereditary hemolytic anemia (282), sickle cell disease (282.6), acquired hemolytic anemia (283), aplastic anemia (284), or unspecified anemias (285). I have sickle cell anemia and I desire to join to military too. You can always ask the recruiter for more questions.
How do the chromosomes of a sperm cell differ from chromosomes in other cells of the body?
They have less chromosomes than a normal cell.
What is the root of anemia?
Usually lack of iron in the diet, which results in the production of less hemoglobin and therefore fewer red blood cells. A deficiency in vitamin B-12 can also cause anemia, as can various afflictions such as thalassemia, sickle-cell syndrome, and some bone cancers.
How is the DNA in the Sickle Cell allele different from the normal allele?
Normally, the 6th position of the beta chain of hemoglobin is a Glutamic acid, encoded on the DNA as GAG. The sickle cell mutation has the sequence GTG, resulting in a Valine in the 6th position instead.
How does the environment affect sickle cell disease?
The blood cells can't carry as much oxygen as they should be able to carry. So the body gets less oxygen.
What causes sickle cell anemia?
Basically, sickle cell anemia means that some of the red blood cells of the person with the disease are not the right shape, instead of being bowl shaped, they are half moon shaped. This means that they can't carry oxygen around the body as well as a person without the condition. As the sickle cells are not only the wrong shape, but also quite rigid, they can block the blood capillaries, so that tissues in the body become starved of oxygen (ischemic). The blockages can vary loads in severity/frequency etc, and they can end up causing a stroke or heart attack if blocking a blood vessel to the brain or heart. One of the organs that is really badly affected by this is the spleen. It has really narrow blood vessels leading to it, so can get starved of oxygen badly and frequently. Normally this means that people with sickle cell anemia do not have a working spleen by the end of childhood, so are at risk of infections. People with sickle cell anemia tend to have more red blood cells than people without the condition as their body over compensates for the red blood cells.
What is an example of a good mutation in genetics?
One example of a beneficial mutation in genetics is the mutation that causes sickle cell anemia. This mutation provides some protection against malaria, making individuals with this mutation less susceptible to the disease.
Sickle cell disease is caused by?
It's caused by a mutation in the hemoglobin gene (a weird change that's basically in the red blood cell).It has to come from two parents who both have a trait of sickle cell. Not all of their kids will have it though. Some kids might have the trait, while some will actually have sickle cell anemia, and some might have no trait of it at all. It's a strange, strange mutation.Sickle cell disease is caused by a point mutation in the gene that codes for hemoglobin which is the primary protein found in the red blood cells. Basically, in the sequence of that gene, one letter changes and causes the entire structure of the hemoglobin molecule to change. The affinity of oxygen to hemoglobin decreases so the mutated red blood cell ends up carrying less oxygen compared to a normal red blood cell.Due to this change, the red blood cell looks like a sickle so its is called a Sickle Cell Disease.
Can anemia lower your ability to fight off infections?
Anemia affects red blood cells usually, and doesn't always lower the immune system response but aplastic anemia (a.k.a bone marrow failure) causes the body to produce less red blood cells, WHITE blood cells, and platelets. Therefore, I believe, anemia can lower your ability to fight off infections (if the amount of white blood cell production is lowered). the above answer is true but people with sickle-cell anemia have a greater resistance to malaria. Also aplastic anemia patients have just as much troube as fighting a VIRUS as any other person.
What does it mean when someone carries the sickle cell gene but does not have the disease?
If you carry the sickle cell gene, it doesn't really mean much as far as your own personal health goes. Except that you are less likely to get malaria. However, if you decide to have kids, and whoever you mate with also carries the sickle cell gene (not the full blown disease/gene) , your child has a chance of having sickle cell disease (full blown).
