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If by Xbox Live you mean Multiplayer then no. There is no online Multiplayer for Mass Effect 2. ME2 is strictly a single player game.
But, you can be connected to Xbox Live and get exclusive offers and DLC's via the XBL Marketplace, that are hard to pass up (if you can pay the price for them :P)
What else can I help you with?
What is the greatest game for xbox 360?
Mass Effect and Mass Effect 2
Mass effect 2 will be on PS3?
No mass effect 2 will only be on xbox 360 and PC
What is a game you should get for your xbox 360?
mass effect 2
What systems are mass effect 2 for?
Currently, it is out for PC and Xbox 360
How do you know about zaeed on mass effect 2?
Zaeed Massani is a mercenary that you can get in your squad via download from The Cerberus Network (requires XBOX Live)
How do you sign out of ea network on mass effect 2?
You can not sign out of the Cerebus Network if you are connected to Xbox Live. If you absolutely do not want to sign into the network, just don't sign into Live.
What can you play mass effect 2 on?
Xbox 360, PC and PlayStation 3
Can you play skyrim mass effect 3 mass effect 2 and mass effect on a 4g Xbox?
Not all of them. Maybe one or two of them, but all four games will not fit on a 4 gig hard drive.
What is mass effect 2 ldc?
You probably mean, DLC. DLC stands for downloadable content. BioWare release DLC for ME2 on xbox live, every so often.
Is mass effect 2 coming out for the PlayStation 3?
Yes, it has already been released for PS3, and when Mass Effect 3 comes out in December 2011, it will be for XBOX, PS3 and PC.
What is an Xbox 360 slim with final fantasy 13 mass effect 2 and modern warfare 2 worth?
$500 tops
Does kaiden die in mass effect 2?
If he died in Mass Effect 1 then he is not in Mass Effect 2. If he survived Mass Effect 1 he shows up in Mass Effect 2 but he can not be killed.
