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Isn't Xylazine when used as an anesthetic induction agent always used with yohimbine as a reversal in veterinary medicine?
Wiki User
∙ 14y ago
Xylazine, an alpha-2 agonist, may be reversed using yohimbine. However, it is not reversed every time it is used. Xylazine (also known by the trade name Rompun) frequently wears off quickly enough that reversal is not needed. This would particularly be true if used as an anesthesia pre-medication prior to propofol or thiopental induction. If xylazine is used as the sole anesthestic induction agent, the duration of the procedure would dictate whether or not yohimbine would be necessary. Yohimbine can also be used to reverse xylazine if a patient's heart rate or blood pressure goes down while under anesthesia and a faster recovery is desired. Combining xylazine with an anticholinergic like glycopyrrolate would help prevent the bradycardia associated with xylazine.
Wiki User
∙ 14y ago
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Is the drug Xylazine like Rohypnol?
Only in the sense that both of them are illegal drugs in the US (Xylazine is approved for veterinary use, but not for human use). The two are not at all similar in structure or mechanism.
What are the effects of Xylazine of you have already ingested it?
you die
How long can rompun be tested in a horse's system?
The drug Rompun (xylazine) has a half life in the horse of 50 minutes. So an hour after you have given a dose 1/2 of the amount given is still in the animals system the next hour 1/2 of that is gone so 1/4 of the original dose is still there the third hour you are down to 1/8th and the fourth hour down to 1/16. You can expect it to be completely cleared in 48 hours. Rompun should NEVER be given by anyone other than a veterinarian! It is NOT a tranquilizer, but and anesthetic/pre-anesthetic and can kill a horse very quickly if you do not know the signs of cardiac/respiratory distress and have yohimbine on hand to reverse the effects!NEVER allow anyone other than a qualified veterinarian or technician to administer this drug to your horse. Lately many farriers have been getting their hands on this drug instead of acepromazine because of its faster acting effects with some really disasterous results. Acepromazine does not effect the hematocrit (Blood oxygen content) when respiration is slower which is NOT true of xylazine.
Can anyone purchase xylazine?
Xylazine is sold by Bayer under the brand name Rompun.-Wikipediai assume it's a prescription drug, so ask a doctor, or go 2 Walgreen's:)don't worry...be happy!
What is the problem if you inject acepromazine and xylazine inject in horse?
No problem if medications are used on healthy horses at the correct dosage for their route Vet schools and "books" will recommend against using "ace" stating it can cause "priapism" in males. Never seen it in 40 years of practice, nor have I heard of any other vet who's had it be a problem It's a good combination, especially if you can't afford detomidine and need a sedative to act longer than the xylazine alone
What is the proper dose for human use of Xylazine IM or IV?
Xylazine is not approved for human use. It's dangerous - accidental exposure in humans has resulted in low blood pressure (hypotension). Do not use it for humans. The person could die. That being said, typical commercially available solutions are 100mg/mL I believe. Typical horse dosage is about 4 mL per 100 kg body weight I think (100 kg = 220 lb.)
What would happen if a person took the drug Xylazine?
It's an animal tranquilizer/sedative. There haven't been any formal human studies, though it's anecdotally known that several people have died from taking it.
What pain relief can you give a mare that's giving birth?
Usually pain medication during the foaling process is unnecessary...and may potentially mask symptoms that indicate that the mare is in need of professional assistance. Post foaling, painful mares can be given certain pain medications such as banamine, xylazine or bute etc...however, these are prescription medications. Unless you have the meds on hand with instructions on their proper use from your vet with regard to this particular foaling mare you may create or mask other issues.
Is carfentanil stronger than methadone?
Carfentanil is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known. Carfentanil, the generic for Wildnil (the combination wild+nil being apropos), is an opioid used in special cases to tranquilize very large wild animals when combined with the sedative Xylazine . Dangerous even with animals, carfentanil is not for human use. This synthetic drug is 100 times stronger than fentanyl; 10,000 times stronger than morphine; 40,000 times stronger than heroin. All things being equal, therefore, as methadone rates in strength between those of fentanyl and morphine, respectively, carfentanil is vastly more potent than methadone without the long-acting effect.
