Only one or two nucleotides are changed in a certain mutation. This is an example of a(n)
Deletion
In a point mutation, a change in a single nucleotide can lead to a specific mutation. For example, a substitution mutation occurs when one nucleotide is swapped for another, such as A to T or C to G. This change can result in different amino acids being coded for in the protein sequence.
This is an example of an insertion mutation. Insertion mutations involve the addition of extra nucleotides into a DNA sequence, which can lead to significant changes in the genetic code and potentially disrupt normal gene function.
This mutation represents a deletion of a single nucleotide (A) in the DNA segment. Deletions involve the removal of one or more nucleotides from the DNA sequence, leading to a change in the genetic code. In this case, the deletion results in a frameshift mutation, causing a shift in the reading frame of the genetic code downstream of the deletion site.
This is an example of a frameshift mutation, where the reading frame of the genetic code is shifted due to an addition or deletion of nucleotides. This can lead to a completely different sequence of codons being read during translation, potentially resulting in a non-functional protein being produced.
One example of a beneficial mutation in genetics is the mutation that causes sickle cell anemia. This mutation provides some protection against malaria, making individuals with this mutation less susceptible to the disease.
A good mutation example is lactase persistence, where individuals can digest lactose into adulthood. A bad mutation example is cystic fibrosis, a genetic disorder that causes severe respiratory and digestive problems.
An insertion mutation is when an extra nucleotide is inserted into the DNA molecule.For example if the original sequence is:AATGCATGGACTan insertion could be:AATCGCATGGACTThis would change the code from: AAT GCA TGG ACTto AAT CGC ATG GAC T.....You can see that after the insertion all the codes are changed. Since each set of three nucleotides codes for an amino acid, this would change all of the subsequent amino acids in the protein coded for by the gene.
PLX4032 is and experimental drug that reserves the effects of a mutation found in certain tumors, it is considered a prime example of the "targeted" cancer therapies of the future
cancer or a tumor
Huntington's disease is an example of a lethal dominant mutation. It is a neurodegenerative disorder caused by a dominant mutation in the HTT gene, leading to progressive loss of motor and cognitive functions, eventually resulting in death.
Mutation occurs where one DNA nucleotide base is changed in the process of DNA replication. These mutations may or may not cause genetic disorders or other observable changes in the organism, but they play a huge role in evolution, cancer, and immune system development.