Maintaining telomere length has been associates with aging.
The enzyme telomerase adds nucleotides to the ends of telomeres thereby maintaining their length.
This enzyme is able to function only until a certain limit, called the Heyflick limit (named after the person who first reported this phenomenon). When the heyflick limit is reached, telomeres cannot be enzymatically lengthened and are programmed for death
Valerie Lindgren has written: 'Chromosome replication in aging and transformed human cells'
Telomeres are the special DNA sequences located at the ends of chromosomes that protect them from deterioration and contribute to aging and cell death when they become too short. Telomeres gradually shorten with each cell division, eventually reaching a critical length that triggers cellular senescence or death.
The end replication problem refers to the gradual shortening of telomeres, which are protective caps at the end of chromosomes, with each cell division. Telomerase is an enzyme that can rebuild telomeres, but its activity is often reduced in aging cells. This leads to cell senescence, reduced tissue repair, and contributes to the aging process in humans.
The end replication problem in eukaryotes refers to the challenge of replicating the ends of linear chromosomes, which leads to the loss of genetic material with each cell division. This impacts DNA replication by causing the gradual shortening of chromosomes over time, which can eventually lead to cell aging and potentially contribute to diseases like cancer.
Aging is the most common form of degenerative disease. It infects everyone and is 100% fatal. Although long looked at as a natural process, there has been significant progress in combating it's effects. It is thought to be caused by a decrease in the length of telomeres in the process of cell replication.
They are apart of our DNA. They protect genes. Alot of research is going into them because there is a theory of thought that says if you can extend your telomers you can live forever. they shorten every time your DNA replicates. Also from smoking lack of exercise and being having alot of fat. studies also show that short telomers are linked to heart diseases and high blood pressure.
The significance of the Texan declaration of independence is that it led to the Mexican-US war and later encouraged the US foreign policy of isolationism
DNA replication begins in areas of DNA molecules are called origins of replication.
aging
intersite replication
"Aging" can either be an adjective (as in, "an aging person") or a gerund (as in, "The person was aging rapidly").
No, the origin of replication is a specific sequence of DNA where the replication process starts, while the replication fork is the Y-shaped structure formed during DNA replication where the DNA strands are unwound and replicated. The origin of replication initiates the formation of the replication fork.