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Except for those who have ulcers or who take medications that could increase the risk of stomach or intestinal bleeding, WebMD does not advise against drinking alcohol while taking prednisone, but the Mayo Clinic advises consulting a doctor first.

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Q: Should you drink alcohol while taking 5 mg prednisone?
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Can you drink wine while taking Prednisone?

There is absolutely no interaction between prednisone and alcohol. You can continue to drink alcohol, safely of course. but prednisone is irritating to the lining of the stomach as is alcohol.


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