it depends
At first Spanish were friendly to them but later dominated them.
The Spanish response to native Americans was generally to either leave them alone or make them slaves. Many tribes were enslaved for plantation and other hard labor.
Pacífico or tranquilo.
the Americans won the Spanish because they have cooler guns and the Spanish don't
Peaceful enough for the times, though the Spanish caused a bit of a stir when they sent their armada to invade Britain. Fortunately, the Spanish forgot our British notorious weather.
Sometimes the Spanish made captured native Americans into slaves
The word 'Sereno" in Spanish means Serene in English which means calm or peaceful.
Spanish
Generally speaking, YES. Spaniards make jokes about Americans like most Non-Americans do, but there is genuine respect and affection. The main hurdle to Spanish-American interaction is the language barrier as most Americans and most Spaniards are monoglots (speakers of only one language).
Americans/ United States
A pacifico is a peaceful native in Cuba or the Philippines who did not oppose Spanish colonization.
They can even be 100% Spanish if they want to.