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Most executive departments, such as the Department of Defense, are headed by a secretary.
The president
Heads of the departments that make up the President's Cabinet are called Secretaries. For example the Department of Labor is headed by the Secretary of Labor, and the Department of Defense is headed by the Secretary of Defense (also abbreviated as SECDEF).
The position of Secretary of War refers to the leader of the War Department. This agency and position was disbanded in the US in 1947, after WWII. The most similar agency in the US is now the Department of Defense, headed by Secretary of Defense Robert Gates.
The US Department of Justice (DOJ or Justice Department) is headed by the Attorney General.
The US Department of Defense (DoD) carries the responsibility for maintaining military competency and preparedness. It is the department responsible for coordinating and supervising all agencies and functions of the government relating directly to national security and the military. The DoD is headed by the Secretary of Defense, who is a civilian appointed by the President.
The yellow headed day lizard hides in bamboo for defense
The Department of Defense is run by the Secretary of Defense.
The Department of Defense is often referred to as The DOD.
The Department of Defense is in charge of the U.S. military.
What is now called the Department of Defense was originally named the Department of War.
The State Department deals with diplomacy while the Department of Defense affiliated with the military.