Hemophilia
factor VIII
Factor VIII is a protein that is typically made in the liver and released into the bloodstream. It is an essential component for normal blood clotting.
Intrinsic pathway of coagulation (measured as PTT in laboratories).
Hemophilia itself is really just a genetic disorder. It causes problems with blood coagulation and people with the disorder tend to bleed a lot if cut, hence the name "bleeders." The disorder is caused by a mutation in the factor VIII gene, leading to a deficiency in factor VIII. (Factor VIII is a protein that is associated with blood clotting.) The deficiency in the blood clotting factor causes the affected person's blood to clot improperly. The factor VIII gene is located on the X-chromosome and is transmitted by recessive inheritance. Males have an X-chromosome and and a Y-chromosome and females have two X-chromosomes. This means that females would only carry one of the mutant alleles for hemophilia and are said to be carriers. Females are usually found to be only carriers and rarely express hemophilia. Males, on the other hand, will receive one X-chromosome from their mother and a Y-chromosome from their father, leading to hemophilia.
There are two types of hemophilia. Type A: A mutation in the factor VIII gene. Type B: A mutation in the IX gene.
Hemophilla is a genetic disorder in which there is absence of clotting factor viii, leading to defective clot formation, petechiae bruising and gum bleeding. Treatment is by injecting factor VIII concentrate
No Factor VIII is Antihemophilic factor.Thrombocytopenia is a low platlet count Thrombocyte = platlet Penia = poorness
i want know price factor viii
factor VIII
Hemophilia
hemophilia |ˌhēməˈfilēə| ( Brit. haemophilia) noun a medical condition in which the ability of the blood to clot is severely reduced, causing the sufferer to bleed severely from even a slight injury. The condition is typically caused by a hereditary lack of a coagulation factor, most often factor VIII.
Factor VIII is a protein that is typically made in the liver and released into the bloodstream. It is an essential component for normal blood clotting.
Hemophilia A is an X-linked, hereditary bleeding disorder caused by the absence or defect of a blood clotting protein, Factor VIII. As a result, when a person with hemophilia A has a bleeding episode, the bleeding may be prolonged due to the body's inability to form blood clots. Patients who are affected with hemophilia A experience frequent spontaneous bleeding, most commonly into their joints and soft tissues, with bleeding into vital organs that may ... be life-threatening. Bleeding episodes may be painful, and over time, recurrent joint bleeding may result in debilitating destruction of the joints. Currently, patients with hemophilia A are dependent on injections of Factor VIII produced by genetic engineering or purified from human plasma, to help control a bleeding episode. It is estimated that approximately 50,000 individuals worldwide are affected with hemophilia A. Hemophilia A - Clotting Factor VIII Hemophilia B - Clotting Factor IX Hemophilia C - Clotting Factor XI
There are a number of factors involved, Condition is the main factor, how old? Which company made them etc.
factor VIII deficienty
50 usd
about 1500 pounds