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affects both initiation and elongation.....
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What is the function of sigma factor in transcription?
when RNA Polymerase meet the correct promoter(TATA box), it will bind at that region and then sigma factor will also bind to the RNA Polymerase.once ATP give energy, sigma factor will dissoiates from RNA Polymerase and the enzyme start to unwind the double helix
What is the attachment site for RNA polymerase?
according to information from http://www.rothamsted.ac.uk/notebook/courses/guide/trans.htm " if the RNA polymerase attaches to a special sequence called a promoter, an additional small protein, the factor sigma, will also attach to the polymerase and lock it on the DNA. The factor 'sigma' will only attach itself to the complex DNA / RNA polymerase when the RNA polymerase is attached to a promoter. Another hypothesis is that the factor sigma attaches to RNApol anyway and the enzyme is then able to slide along the DNA until it finds a promoter. It prevents detaching and speeds up promoter location, and decreases the affinity of RNApol for general regions of DNA. " Therefore, the answer seems to be, RNA attaches to DNA through a small protein called the factor sigma once the RNA polymerase attaches itself to a chain sequence called a "promoter". according to information from http://www.rothamsted.ac.uk/notebook/courses/guide/trans.htm " if the RNA polymerase attaches to a special sequence called a promoter, an additional small protein, the factor sigma, will also attach to the polymerase and lock it on the DNA. The factor 'sigma' will only attach itself to the complex DNA / RNA polymerase when the RNA polymerase is attached to a promoter. Another hypothesis is that the factor sigma attaches to RNApol anyway and the enzyme is then able to slide along the DNA until it finds a promoter. It prevents detaching and speeds up promoter location, and decreases the affinity of RNApol for general regions of DNA. " Therefore, the answer seems to be, RNA attaches to DNA through a small protein called the factor sigma once the RNA polymerase attaches itself to a chain sequence called a "promoter". role of sigmaActually RNA Polymerase can bind to DNA anywhere in the entire genome but sigma factor attaches to polymerase only when it is at promotor. sigma factor dissociates when polymerase crosses promotor. sigma factor stablises the pre initiatiation complex. Actually there are many promoter and many genes but which gene to be transcribed is decided by sigma factor.
What does sigma factor assits?
A sigma factor (σ factor) is a protein needed only for initiation of RNA synthesis.
Is RNA primer in translation?
RNA polymerase's main job is to transcribe mRNA from double stranded DNA. It does so by recognizing promoter region in ds DNA and binds over there. Sigma factor is a subunit of RNA polymerase that helps in locating promoter region. RNA polymerase simply synthesized complimentary base pairs from DNA template and makes mRNA. so there is no need of primer at all.
What is the subunit structure of the core RNA polymerase enzyme?
Core enzyme is composed of 2 alpha sub-units 2 beta sub-units (polymerase activity and clamp). Holoenzyme is the same with sigma factor attached which binds to prinbow box in mRNA.
What enzyme binds to DNA and is responsible for making a transcript RNA of DNA?
RNA mRNA tRNA
What are the different types of RNA polymerases and their promoters?
rma polymerase 1, rna polymerase 2, rna polymerase 3
What enzyme transcribes DNA?
The enzyme that transcribes the DNA into RNA is called RNA polymerase.
What is the name of the enzyme that creates mRNA?
RNA polymerase is the enzyme that makes mRNA from a strand of DNA.
Where does RNA polymerase blind?
The RNA polymerase binds to the promoter. RNA stands for ribonucleic acid.
What enzyeme helps a cell to make a strand of rna?
RNA polymerases
Is the enzyme that allows replication to occur DNA polymerase or RNA polymerase?
DNA polymerase replicated DNA. RNA polymerase creates mRNA to be used in protein synthesis. RNA polymerase does not replicated DNA.
