affects both initiation and elongation.....
when RNA Polymerase meet the correct promoter(TATA box), it will bind at that region and then sigma factor will also bind to the RNA Polymerase.once ATP give energy, sigma factor will dissoiates from RNA Polymerase and the enzyme start to unwind the double helix
according to information from http://www.rothamsted.ac.uk/notebook/courses/guide/trans.htm " if the RNA polymerase attaches to a special sequence called a promoter, an additional small protein, the factor sigma, will also attach to the polymerase and lock it on the DNA. The factor 'sigma' will only attach itself to the complex DNA / RNA polymerase when the RNA polymerase is attached to a promoter. Another hypothesis is that the factor sigma attaches to RNApol anyway and the enzyme is then able to slide along the DNA until it finds a promoter. It prevents detaching and speeds up promoter location, and decreases the affinity of RNApol for general regions of DNA. " Therefore, the answer seems to be, RNA attaches to DNA through a small protein called the factor sigma once the RNA polymerase attaches itself to a chain sequence called a "promoter". according to information from http://www.rothamsted.ac.uk/notebook/courses/guide/trans.htm " if the RNA polymerase attaches to a special sequence called a promoter, an additional small protein, the factor sigma, will also attach to the polymerase and lock it on the DNA. The factor 'sigma' will only attach itself to the complex DNA / RNA polymerase when the RNA polymerase is attached to a promoter. Another hypothesis is that the factor sigma attaches to RNApol anyway and the enzyme is then able to slide along the DNA until it finds a promoter. It prevents detaching and speeds up promoter location, and decreases the affinity of RNApol for general regions of DNA. " Therefore, the answer seems to be, RNA attaches to DNA through a small protein called the factor sigma once the RNA polymerase attaches itself to a chain sequence called a "promoter". role of sigmaActually RNA Polymerase can bind to DNA anywhere in the entire genome but sigma factor attaches to polymerase only when it is at promotor. sigma factor dissociates when polymerase crosses promotor. sigma factor stablises the pre initiatiation complex. Actually there are many promoter and many genes but which gene to be transcribed is decided by sigma factor.
The sigma factor is a protein that helps RNA polymerase bind to the promoter region of a gene during transcription. It plays a crucial role in initiating the process of transcription by guiding RNA polymerase to the correct starting point on the DNA strand.
The sigma factor of RNA polymerase helps to recognize and bind to specific DNA sequences, known as promoters, to initiate the process of transcription. It plays a crucial role in determining which genes are transcribed and when they are transcribed in a cell.
The sigma factor is a protein that helps RNA polymerase bind to specific DNA sequences, known as promoters, to initiate gene transcription. It plays a crucial role in determining which genes are transcribed and when they are transcribed in a cell.
A sigma factor (σ factor) is a protein needed only for initiation of RNA synthesis.
No, RNA polymerase is not considered a transcription factor. RNA polymerase is an enzyme responsible for catalyzing the synthesis of RNA from a DNA template during the process of transcription. Transcription factors are proteins that regulate the transcription of specific genes by binding to DNA sequences.
RNA polymerase's main job is to transcribe mRNA from double stranded DNA. It does so by recognizing promoter region in ds DNA and binds over there. Sigma factor is a subunit of RNA polymerase that helps in locating promoter region. RNA polymerase simply synthesized complimentary base pairs from DNA template and makes mRNA. so there is no need of primer at all.
The enzyme that transcribes the DNA into RNA is called RNA polymerase.
RNA polymerase is the enzyme responsible for binding to DNA and synthesizing a complementary RNA strand during transcription.
There are three different types of RNA polymerases in eukaryotic cells: RNA polymerase I, II, and III. Each type is responsible for transcribing a specific set of genes. RNA polymerase I transcribes ribosomal RNA genes, RNA polymerase II transcribes protein-coding genes, and RNA polymerase III transcribes small structural RNA genes. The promoters for each type of RNA polymerase are different and contain specific sequences that are recognized by the polymerase to initiate transcription.
RNA polymerase is the enzyme that makes mRNA from a strand of DNA.