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The growth of MALT lymphomas is dependent upon what factor?

Updated: 8/19/2019
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GaleEncyofMedicine

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13y ago

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Their growth seems to be dependent upon continuous stimulation of the immune system by an infectious agent, such as H. pylori, or some other entity, termed an antigen, that the body recognizes as foreign.

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Q: The growth of MALT lymphomas is dependent upon what factor?
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What symptoms are associated with MALT lymphomas?

MALT lymphomas are generally indolent, that is, they grow slowly and cause little in the way of symptoms.


What causes MALT lymphomas outside the stomach?

It is not known if infectious agents also cause MALT lymphomas outside of the stomach.


How are MALT lymphomas recognized in an endoscopy examination of the stomach?

MALT lymphomas are then recognized as areas of inflammation or ulceration within the stomach.


What is the occurrence of MALT lymphomas in the general population?

MALT lymphomas occur at a frequency of about 1.5 per 100,000 people per year in the United States and account for about 10% of all non-Hodgkin's lymphomas.


How can MALT lymphomas be treated?

This antigen-driven growth permits these tumors to be treated by eliminating the stimulus that generated the original, normal immune response.


How are MALT lymphomas in the stomach treated?

Those MALT lymphomas that arise in the stomach in response to H. pylori infections are generally successfully treated with antibiotics, which eliminate the bacteria.


Where in the body does a MALT Lymphoma most commonly occur?

MALT lymphomas are solid tumors that originate from cancerous growth of immune cells that are recruited to secretory tissue such as the gastrointestinal tract, salivary glands, lungs, and the thyroid gland.


What is the best staging area for the evaluation of patients with MALT lymphomas?

it is standard practice that patients presenting with MALT lymphomas should be evaluated in a similar manner to individuals with nodal lymphomas, the more common type of lymphoma that originates at sites within the lymphoid system.


What individuals may be at increased risk to develop MALT lymphomas?

In some cases, such as in the thyroid, MALT lymphomas seem to arise in patients who have autoimmune diseases, which make their immune systems treat their own tissue as foreign or antigenic.


In what global region is there a higher than average occurrence of MALT lymphomas?

The frequency varies among different populations. For example, in parts of Italy the frequency of MALT lymphomas is as high as 13 per 100,000 people per year.


What portion of US patients with H.pylori infections develop MALT lymphomas?

In the United States, where infections with H. pylori are quite common, less than 1 in 30,000 people who have H. pylori in their stomachs develop MALT lymphomas.


In what global region is there a higher than average occurence of MALT lymphomas?

The frequency varies among different populations. For example, in parts of Italy the frequency of MALT lymphomas is as high as 13 per 100,000 people per year.