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What chromosome has been identifed with a familial predisposition to malignant melanoma?
Chromosome 9p has been identified as being involved in familial predisposition.
What chromosome has been identified with a familial predisposition to malignant melanoma?
Chromosome 9p has been identified as being involved in familial predisposition.
What factors create a predisposition to malignant melanoma?
Factors that create a predisposition to malignant melanoma include a family history of the disease, having fair skin that burns easily, a history of excessive sun exposure or sunburns, having numerous moles or atypical moles, and a weakened immune system. Additionally, individuals with a personal history of melanoma or other types of skin cancer are also at an increased risk.
How does a family history of malignant melanoma impact the predisposition for malignant melanoma?
A positive family history of one or two first-degree relatives having had melanoma substantially increases the risk on a genetic basis. A family tendency is observed in 8% to 12% of patients.
Where does malignant melanoma develop?
Malignant melanoma may develop anywhere on the body.
What reading material is available on the diagnosis and prognosis of malignant melanoma?
Carlson, J. A., A. Slominski, G. P. Linette, et al. "Malignant Melanoma 2003: Predisposition, Diagnosis, Prognosis, and Staging." American Journal of Clinical Pathology 120 , Supplement (December 2003): S101-S127.
What epidermal layer does malignant melanoma arise?
Malignant melanoma arises in the Stratum basale layer of the epidermal layer.
Is melanoma dominant or recessive?
is malignant melanoma dominant or recessive
How many forms of malignant melanoma exist?
Malignant degeneration of the melanocyte gives rise to the tumor known as melanoma, which has four subtypes.
What is the clinical staging of malignant melanoma based on?
Malignant melanoma is locally staged based on the depth of penetration through the skin and its appendages.
What is a malignant melanoma?
skin tumour/cancer
What kind of metastasis can occur regionally in malignant melanoma?
There is also a special type of metastasis that can occur regionally with malignant melanoma; it is known as an in-transit metastasis.
