By plane. If you are driving, I5 would be the quickest, most direct route.
The A1 motorway.
I-65 SOUTH (from INDIANA).
The quickest route is 1,958 miles.
maps.google.com
The quickest driving route to Eliat from Jerusalem is 308 km
The shortest and the quickest route is I-85 N.
I-75 to Chattanooga, I-24 to Nashville, I-65 to Gary, IN, and I-90 into Chicago.
The route with the shortest driving time is about 1,510 miles.
The quickest route is about 493 miles. The longest is about 524 miles.
Take I-94 WEST to I-80 WEST.Take I-80 WEST to San Francisco.
It depends on the route you take but the approximate driving distance (using major roadways) is 1,740 miles.