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Penicillin is a normal product of fungal metabolism that is capable of killing germs(bacteria).Penicillium notatum was the first fungal species from which penicillin was isolated.Production involves fermentation of the fungal spores in carefully -regulated nutrient media.
The nutrients consists of glucose and nitrogen-source,phosphate and calcium in addition to minerals(phenyl-acetic acid) which helps to make the penicillin molecule.
Penicillin is the secondary metabolite that is produced after the initial rapid growth phase of the fungus.The primary metabolites include carbon dioxide and ethanol from respiration.
The temperature and pH(6.5-7) are carefully regulated as production is very sensitive to temperature. The fungus mycelium is then removed by filtration and the penicillin remains behind in solution in the liquid part of the medium.
All impurities are then removed by extraction and vacuum to leave penicillin as a sodium or potassium salt.
Wiki User
∙ 12y ago
Wiki User
∙ 11y agoadmin kardeş ben de onun cevabını arıyodum da. :s yk hç bi yrdee .s
Wiki User
∙ 7y agoPenicillin is produced from the fungus penicillium. Actively dividing cells do not produce penicillin. When the stress is given to the fungus, it produce the antibiotic.
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It was the first company to successfully mass produce penicillin. It was about 1945 towards the close of WWII. Limited quantities were available prior to that, and infection typically killed more soldiers than the direct effect of the gunshot itself.
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