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Depressants are drugs that decrease the nervous system's activity. The nervous system uses many types of molecules, called neurotransmitters, to send signals back and forth throughout the body. Most drugs that are depressants exert their effects by increasing the activity of a neurotransmitter called GABA, short for gamma-aminobutyric acid. Some depressants are used clinically to treat anxiety disorders and insomnia. and contrary to popular beliefs Marijuana is a Cannabinoid not a depressant

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