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They are used for their unique properties as carriers of other molecular structures, in order to improve the activity and efficiency of an active drug molecule and also to reduce unwanted effects. Their molecular structure of these entities have great desire shape.
Within a dendrimer, its physical and physiological properties remains unaltered, including non-specificity and their unwanted effects.
- Results from these research has shown that dendrimers have increased aqueous solubility, slowed release rate, and possibly reduce unwanted effects of the drugs (they can lower drug resistance)
What else can I help you with?
How does a solubility curve work?
A solubility curve shows how the solubility of a substance changes with temperature. It plots the amount of solute that can dissolve in a specific amount of solvent at different temperatures. As temperature increases, solubility typically increases for solid solutes but can decrease for gases. Understanding the solubility curve can help predict how much of a substance will dissolve under different conditions.
Application of solubility in pharmacy?
In pharmacy, solubility is critical for drug formulation and delivery, as it affects the bioavailability of medications. Drugs must dissolve in bodily fluids to be absorbed effectively, making solubility a key factor in determining the onset and intensity of therapeutic effects. Pharmaceutical scientists often optimize solubility through various techniques, such as using solvents, adjusting pH, or employing solubilizing agents to enhance drug effectiveness. Additionally, understanding solubility helps in predicting drug interactions and stability in formulations.
Why solubility is important in the medical field?
Solubility is crucial in the medical field because it directly affects the absorption and bioavailability of drugs in the body. Medications must dissolve in bodily fluids to be effectively transported to target sites, ensuring therapeutic efficacy. Poor solubility can lead to inadequate drug delivery, reduced effectiveness, and increased variability in patient responses. Additionally, understanding solubility helps in the formulation of drugs and the development of delivery systems, optimizing treatment outcomes.
What is the BCS class of drotaverine hydrochloride?
Drotaverine hydrochloride is classified under the Biopharmaceutical Classification System (BCS) as a Class II drug. This indicates that it has high permeability but low solubility. As a result, its absorption can be influenced by the solubility characteristics, making formulation and administration considerations important for effective therapeutic use.
What are the advantage and disadvantage of solubility?
Advantage: Solubility allows for the efficient dissolution and mixing of substances, enabling reactions to occur and facilitating transport within organisms. Disadvantage: In some cases, solubility can lead to environmental pollution when substances dissolve and spread in water bodies, causing harm to ecosystems.
What are the advantages of storing acid in polyethylene plastic bottle?
- the polyethylene plastic bottle is unbreakable- the glass has a solubility (low and dependent on the type of glass) in acids
Difference between therapeutic and non therapeutic technique?
Therapeutic is an immediate physical treatment, non-therapeutic is a treatment such as sterilisation
The ability of a substance to dissolve in a solvent is called?
The ability of a solute to dissolve in a solvent at a certain temperature is called solubility. The solubility of most solids in water increases with temperature increases.
What are advantages and disadavantages of powder?
Advantages of powder include longer shelf life, ease of transportation, and potential for controlled dosage. Disadvantages may include messiness during handling, potential inhalation hazards, and limitations in terms of solubility in certain applications.
Why is theophylline combined with sodium acetate?
Theophylline is combined with sodium acetate to create a buffer system that maintains the pH and stability of the medication. This combination helps improve the solubility and absorption of theophylline in the body, leading to better therapeutic outcomes.
How would you define the therapeutic dosage?
The therapeutic dosage is the amount of a therapeutic agent which causes the therapeutic effect. This is prescribed by qualified therapists for varied conditions.
What is the ability of one material to dissolve in another?
The ability of one substance to dissolve in another substance is called SOLUBILITY.
