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What Chemicals are in Cociane?

Updated: 10/26/2022
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12y ago

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If you meant cocaine

Cocaine (benzoylmethylecgonine) (INN) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant.

Street market cocaine is frequently adulterated or "cut" with various powdery fillers to increase its weight; the substances most commonly used in this process are baking soda; sugars, such as lactose, dextrose, inositol, and mannitol; and local anesthetics, such as lidocaine or benzocaine, which mimic or add to cocaine's numbing effect on mucous membranes. Cocaine may also be "cut" with other stimulants such as methamphetamine. Adulterated cocaine is often a white, off-white or pinkish powder.

Synthetic Cocaine ('bath salts') on the other hand is a mixture of chemicals, far more dangerous than the 'natural' cocaine.

The synthetic and regular versions look the same but the former is more dangerous than the latter. As proof to this, a 20-year old man who contacted ABC said that people taking synthetic cocaine feel a different high in that people under its influence feel they are on top of the world once they have ingested the drug. As soon as they are out of the hype, they crave for more.

Making synthetic cocaine requires a significantly high level of synthetic expertise and well-equipped laboratory facilities. The process requires 5 steps.

Some of the chemicals needed (a partial list) are methylamine, succindialdehyde, and acetonedicarboxylic acid monomethyl ester, 2-carbomethoxytropinone, hydrochloride.

The clandestine manufacture of illicit synthetic cocaine is extremely unusual. This is not surprising, because - even when attempted by a skilled chemist - the preparation of (-)-cocaine via total synthesis proceeds in less than 10% overall yield. This is clearly economically infeasible in view of the relatively low cost and ready availability of illicit natural cocaine.

The purity of uncut illicit synthetic cocaine can vary dramatically depending on the skill of the clandestine operator performing the synthesis. Illicit synthetic cocaine will not contain many of the alkaloidal impurities commonly identified in illicit natural cocaine, e.g., trimethoxycocaine, the cinnamoylcocaines or the truxillines, but can include any of a wide variety of synthetic by-products

Of these, pseudococaine, benzoyltropine and tropacocaine, resulting from benzoylation of pseudoecgonine methyl ester, tropine and pseudotropine, respectively, are the most likely.

Additional impurities which are indicative of synthetic cocaine include 3-benzoyloxy-2-carbomethoxytropidine (2,3-didehydrococaine), 3-benzoyloxytropidine (2,3-didehydrotropacocaine), and 2-carbomethoxy-3-methylaminotropidine22. 2,3-Didehydrococaine and 2,3-didehydrotropacocaine result from the benzoylation of unreduced 2-carbomethoxytropinone and tropinone, respectively, and 2-carbomethoxy-3-methylaminotropidine from the irreversible rearrangement of the 2-carbomethoxytropinone/methylamine imine formed during the initial Mannich condensation reaction.

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