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The Mayflower originally departed from the English port of Southampton in August 1620, accompanied by a smaller vessel the Speedwell. Because the Speedwell was leaking, the ships were forced to return first to Dartmouth and then to Plymouth.

The Mayflower finally set sail alone from Plymouth, England, in September 1620 for the 66-day voyage to the American site that the Puritan settlers also named Plymouth.

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Wiki User

14y ago
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Anonymous

Lvl 1
3y ago
The Mayflower was engaged by people fleeing religious persecution in England in Boston, Lincolnshire, England. They sailed from Boston with the eventual last port of call in England being Plymouth. Get you facts right.
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Anonymous

Lvl 1
3y ago
There is a Church in Boston ( England) called The Boston Stump which is dedicated to those who chartered the vessel and sailed on it. 

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Q: What English seaport did the Mayflower sail from?
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