I know Brock, and probally Misty. Possibly Giovanni
you beat them in a battle
beat all battle frontier leaders
You go around map. beat the gym leaders and collect pokemon. battle other people and level and evolve your pokemon.
well you cant battle them again but in another Pokemon game you can and they are easy to beat and after you beat them you get like 6586 dollars cool huh?
You have to beat the battle brains (6) which are like super hard gym leaders. You can always battle there again whenever you want to.
You have to beat all gym leaders and the Elite 4 and Champion.
beat 8 gum leaders and go to every grane city
yes you have to beat all the colussem leaders 80 times
just beat ash kanto gym leaders andkanto elite four i did it and it workt
Once you beat the Elite 4 you can battle gym leaders in the Kanto region. Also once you beat red you can get a Kanto starter. Good Luck!!
beat the battle frontier, collect every gym leaders pokegear number and beat them at level 100. then your done. also get mewtwo in cerulean cave.
Beat Mt. Battle Twice and go to Relgam tower beat it, Then Deoxeys will show up in your PC.