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What antiemetics are contraindicated with Parkinson's Disease?
Wiki User
∙ 11y ago
Any antiemetic drug that can cause extrapyramidal symptoms (or whose mechanism relies on dopaminergic antagonism such as domperidone, metoclopramide etc) should be absolutely avoided in patients with PD. Certain H1 blocking antiemetics such as cyclizine can cause EPS hence always check wirh your Phramcist or Physician before taking any of these medicines. Anti emetics that can be safely given to PD patients include the setron family of 5HT-3 antagonists. Also, diphenhydramine (BENADRYLTM) an H1 antihistaminic is free from EPS therefore, it can also be used safely for nausea and vomiting in PD patients.
Wiki User
∙ 11y ago
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