Tay-Sachs is caused by a defective gene. Genes are located on chromosomes, and serve to direct specific development/processes within the body. The genetic defect in Tay-Sachs disease results in the lack of an enzyme called hexosaminidase A.
The defective gene that causes Tay-Sachs disease is found in roughly 1 in 250 people in the general population.
Multiple mutations are responsible for Tay Sachs Disease. For example, Tay Sachs in the french Canadian population may be due to a different mutation then people of eastern European Jewish descent with Tay Sachs. any mutation that causes the absence of the enzyme Hexosamindase (Hex-A) is a mutation that can cause a Tay Sachs genotype/phenotype within an individual
It was named after doctors Warren Tay and Bernard Sachs.
Tay-Sachs disease eventaully causes the child to develops problems with breathing and swallowing. Blindness, paralysis, and death follow.
The DNA sequence of the allele that causes Tay-Sachs disease is different from that of the normal allele. This difference in the DNA sequence allows for specific genetic tests to be conducted to identify the presence of the Tay-Sachs disease allele in individuals.
what effect does Tay-sachs disease have on the body?
Tay-Sachs disease is a human genetic disorder.
Tay-Sachs disease is a genetic disorder that causes progressive neurological deterioration. It typically manifests in infancy and leads to developmental delays, seizures, and loss of motor skills. Sadly, most individuals with Tay-Sachs do not live past early childhood.
A person with tay sachs can live a healthy life but still battles the many limitations of Tay sachs disease. Depending on the type of tay sachs, Classic, Juvenile onset, and Late Onset depends how healthy a life a person with tay sachs disease.
A mutation of the HEX A gene of chromosome 15 causes Tay-Sachs disease. As a result, the protein hexosaminidase A is not formed properly and GM2 ganglioside, the lipid normally broken down by hexosaminidase A, accumulates to toxic levels (especially in the brain).
There are a couple ways Tay-Sachs can be prevented; 1) determine if both you and your mate carry the Tay-Sachs gene 2) perform a prenatal diagnosis to determine if the fetus carries the Tay-Sachs gene Hope this helped!
There is no evidence that shows that tay-sachs is a sex-linked trait.