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Some examples of infectious prion diseases include scrapie in sheep and goats, kuru in cannibalistic humans of Papua New Guinea, and BSE, or mad cow disease, which is transmitted to humans through infected beef products.
Alzheimer's Disease is a transmissible prion/protein disease.
Researchers injected mice with brain matter from an AD victim and the mouse developed brain lesions.(Jucker, Walker, 2010)
betaamyloidcjd.blogspot.com/2010/08/transcellular-spread-of-cytosolic.html
David Colby & Stanley Prusiner - Released January 2011 ENLARGING SPECTRUM OF PRION-LIKE DISEASES
cshperspectives.cshlp.org/content/3/1/a006833.full.pdf+html
"The discovery that prions form amyloid prompted one of us to suggest that the common neurodegenerative diseases are also caused by prions (Prusiner 1984; Prusiner 2001) despite the inability to transmit such illnesses to monkeys and apes (Goudsmit et al. 1980).
"Taken together, these findings argue that prion-like, self-propagating states feature in many different, if not all, neurodegenerative diseases."
Regarding transmission to monkeys and apes, in 2007 in the UK, researchers injected marmosets with AD brain homogenates, and some of the animals developed AD-like amyloid plaques (Baker, Ridley, et al 2007) kxnet.com/getForumPost.asp?setCity=bis&ArticleId=113652
Alzheimer's is a prion disease: sludgevictims.com/pathogens/ALZHEIMERS_is_a_prion_disease.pdf
Recently Nobel Laureate Stanley Prusiner and Dr. Warren Olanow said Parkinson's Disease (PD - 1 million victims) is also most likely a prion disease:
"It is thus possible that PD is a prion disorder resulting from increased production and/or impaired clearance of
proteins such as a-synuclein, leading to misfolding and the formation of toxicoligomers, aggregates, and cell death.
Further, it is possible that a-synuclein is a prion protein that can self-aggregate and be transmitted to unaffected cells, thus extending the disease process.'
pnas.org/content/106/31/12571.full
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How serious is prion disease?
All prion diseases are inevitably fatal; there are no known cures.
How do people get sporadic prion disease?
Patients with sporadic prion diseases may have a susceptibility polymorphism in their PRNP gene, and may have spontaneous mutations forming prion proteins.
Is a virus a prion?
No, although there is a hypothesis that prion diseases are associated with an undetected viral pathogen.
What is the treatment for prion disease?
There is no known effective treatment to arrest or cure prion diseases. Treatment focuses on alleviating the patient's symptoms, increasing their comfort, and palliative care.
What is a hereditary form of prion disease?
Prion diseases can also be hereditary, as seen in some cases of Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), and Gerstmann-Straussler-Scheinker disease (GSS).
Is a prion a virus?
No, although there is a hypothesis that prion diseases are associated with an undetected viral pathogen.
How serious is prion disease?
All prion diseases are inevitably fatal; there are no known cures.
How do people get sporadic prion disease?
Patients with sporadic prion diseases may have a susceptibility polymorphism in their PRNP gene, and may have spontaneous mutations forming prion proteins.
What is a well known prion disease?
There are multiple prion diseases, including bovine spongiform encephalopathy (BSE), or "mad cow disease."
Is a virus a prion?
No, although there is a hypothesis that prion diseases are associated with an undetected viral pathogen.
What is the treatment for prion disease?
There is no known effective treatment to arrest or cure prion diseases. Treatment focuses on alleviating the patient's symptoms, increasing their comfort, and palliative care.
What diseases can you catch?
infectious diseases (those with bacterial or virus, or prion) you can also "catch" chemical based diseases such as contamination burns if you come into contact with someone with the chemicals on them.
What are 4 different kinds of phatogen?
Bacterium, prion, virus, virus, and fungus are 4 different types of pathogens. Pathogens are things that tend to cause diseases in their hosts. Hosts can be plants, animals, or humans.
What one of these is an infectious protein?
They are called Prion. This is the definition I fount at wordnetweb.princeton.edu/perl/webwn: "an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system".
What is a hereditary form of prion disease?
Prion diseases can also be hereditary, as seen in some cases of Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), and Gerstmann-Straussler-Scheinker disease (GSS).
Is mad cow disease in the blood of cows?
No. Bovine spongiform encephalopathy (BSE, the scientific name for mad cow disease) is caused by a misfolded protein called a prion. The protein has been found in the distal small intestine, tonsils and central nervous system tissues of cattle infected with the prion. The prion has never been found in the blood or milk of cattle.
Who first studied prion disease?
Research on prion diseases was founded by Dr. Stanley Prusiner, a neurologist at the University of California San Francisco. He spent two decades working on the revolutionary topic of self-reproducing prions.
