The blood cell begin their lives in the bone marrow from a single type of cell called pluripotent hematopoietic stem cell.All the circulating blood cells are eventually derived from PHSC.
Undifferentiated cells are known as stem cells. These cells have the potential to develop into different types of specialized cells in the body through a process called differentiation. Stem cells are found in various tissues and can be used for research and regenerative medicine.
There are two other sources of hematopoietic stem cells--bone marrow and peripheral blood
Multipotent hematopoietic stem cells
Hematopoietic stem cells are the ancestors of all blood cells. These cells have the ability to differentiate into various types of blood cells, such as red blood cells, white blood cells, and platelets.
The three types of stem cells in adults are hematopoietic stem cells (found in bone marrow and produce blood cells), mesenchymal stem cells (found in various tissues like bone marrow and fat, can differentiate into bone, cartilage, and fat cells), and neural stem cells (found in the brain and spinal cord, can differentiate into neurons and supporting cells).
Hematopoietic stem cells are the parent cells for all formed elements of blood, including red blood cells, white blood cells, and platelets. These stem cells have the ability to differentiate into various specialized blood cells through a process called hematopoiesis.
Erythrocytes are formed from stem cells called hematopoietic stem cells, which are found in the bone marrow. These stem cells have the ability to differentiate into various blood cell types, including red blood cells (erythrocytes).
Neutrophils of the blood are derived from a population of stem cells called hematopoietic stem cells. These stem cells are located in the bone marrow and have the ability to differentiate into various types of blood cells, including neutrophils.
Richard T. Maziarz has written: 'Blood and marrow transplant handbook' -- subject(s): Hematopoietic Stem Cell Transplantation, Transplantation, Hematopoietic stem cells, Nursing
Bone marrow contains hematopoietic stem cells that can differentiate into various types of blood cells, such as red blood cells, white blood cells, and platelets. These stem cells undergo a process of differentiation and maturation to produce the different types of blood cells needed for proper functioning of the immune system and oxygen transport in the body.
In adults, the stem cells responsible for replacing old blood cells are primarily found in the bone marrow. These hematopoietic stem cells (HSCs) have the ability to differentiate into various types of blood cells, including red blood cells, white blood cells, and platelets. Additionally, some hematopoietic stem cells can also be located in peripheral blood and the spleen, but the bone marrow remains the main site for adult blood cell production.
Stromal cells provide structural support to tissues and organs, regulate cell behavior, and help maintain the microenvironment where cells interact. They also play a critical role in wound healing, immune response, and maintaining tissue homeostasis.