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What are some examples of ACE II inhibitors?

Updated: 10/19/2022
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GaleEncyofMedicine

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13y ago

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losartan (Cozaar), candesartan (Atacand), irbesartan (Avapro), telmisartan (Micardis), valsartan (Diovan) and eprosartan (Teveten) directly inhibit the effects of ACE II rather than blocking its production.

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Q: What are some examples of ACE II inhibitors?
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Related questions

Is micardis an ace inhibitor?

No, Micardis is an ARB (angiotensin II receptor blocker). ACE inhibitors reduce the production of Angiotensin-II, whereas ARBs block them from binding to receptors on cell walls).


What is use of ACE inhibitors?

ACE inhibitors lower your blood pressure. For the fuller story, see below... "ACE" is an acronym for Angiotensin Converting Enzyme. The liver makes an enzyme called Angiotensinogen. This is modified by another enzyme (renin), and is then renamed Angiotensin I. Its changed into its functional form, Angiotensin II, by ACE (formed in the lungs). Among its other functions, Angiotensin II constricts or narrows the diameter of blood vessels, making blood pressure go up. So, an ACE inhibitor, slows down the conversion of Angiotensin I into Angiotensin II, resulting in lower blood pressure.


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What are ACE enzymes?

ACE stands for Angiotensin Converting Enzyme. Angiotensin II is the most potent vasoconstrictor in your body. In order to get from Angiotensin I to Angiotensin II, there is an enzyme required for this reaction to occur. ACE inhibitors are used to treat high blood pressure (and congestive heart failure) and they exert their effect by blocking the enzyme.


Why should ACE II inhibitors not be used by pregnant women?

Drugs that act directly on the renin-angiotensin system can cause fetal and neonatal morbidity and death when administered to pregnant women.


Is diovan an ace inhibitor?

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Why ACE inhibitor contraindicated in renal artery stenosis?

In the presence of renal artery stenosis, the resistance in the afferent arteriole is increased. As compensation, Angiotensin II acts to constrict the efferent arteriole in order to achieve adequate profusion of the glomerulus. ACE inhibitors block the conversion of angiotensin I into angiotensin II. Without its vasoconstrictive effect, the efferent arteriole becomes dilated. This leads to a drop in GFR and may lead to renal failure.


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CortisolReninAn over-active renin-angiotension system leads to vasoconstriction and retention of sodium and water. These effects lead to hypertension. Therefore, renin inhibitors can be used for the treatment of hypertension. This is measured by the plasma renin activity (PRA).In current medical practice, the renin-angiotensin-aldosterone-System's overactivity (and resultant hypertension) is more commonly reduced using either ACE inhibitors (such as ramipril and perindopril) or angiotensin II receptor blockers (ARBs, such as losartan, irbesartan or candesartan) rather than a direct oral renin inhibitor. ACE inhibitors or ARBs are also part of the standard treatment after a heart attack.


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