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by bacterial endotoxins,

rapid and dangerous fevers.

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13y ago
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6mo ago

Some examples of pyrogens are bacterial endotoxins, such as lipopolysaccharides (LPS) found in the outer membrane of gram-negative bacteria, and certain viral and fungal components. These substances can induce fever by activating immune cells to release cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α), which then act on the hypothalamus to raise body temperature.

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Q: What are some examples of pyrogens?
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What are pyrogens?

A substance that produces a fever. The hypothalamus senses temperature changes, a thermoreceptors. And a hypothalamic "thermostat" sends signals to increase or decrease temperature. Pyrogens are chemicals that increase the hypothalamic temperature setpoint. And therefore permit fever. some bacterial toxins produce Pyrogens so we get fever when we have bacterial infection.


What compound promotes a fever?

Pyrogens


High level of pyrogens in blood indicate?

circulating proteins called Pyrogens can reset this themostat and raise body temperature "fever"


Do pyrogens act by increasing the set point for body temperature in the thalamus?

No. Pyrogens act by increasing the temperature, but they do not change the set point in the thalamus.


What is the function of pyrogens?

inhibit bacterial growth


What is heat labile depyrogenation?

Pyrogens that are destroyed by heat.


Can pyrogens handle body temperatures that are above normal?

No


Why are aspirin and Ibuprofen anti pyrogens?

they reduce fever


The circulating substances that affect the hypothalamus and initiate fever are?

pyrogens


What are The circulating substances that affect the hypothalamus and initiate fever?

Pyrogens


Why is there fever with pancreatitis?

Microorganisms, including bacteria and parasites, can produce chemical poisons. Both the microorganism and the poisons cause the white blood cells (called monocytes) to produce substances called pyrogens. It's the pyrogens that actually cause fever. The body produces pyrogens in response to infection, inflammation, cancer, or an allergy. The word pancreatitis literally means inflammation or infection of the pancreas so your body's natural response to send those pyrogens after it thus causing fever.


The body's temperature-regulating thermostat that can be reset upward in response to pyrogens is located in the?

Hypothalamus