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Signs and symptoms of mononucleosis may include:

  • Fatigue
  • Weakness
  • Sore throat, perhaps a strep throat that doesn't get better with antibiotics
  • Fever
  • Swollen lymph nodes in your neck and armpits
  • Swollen tonsils
  • Headache
  • Skin rash
  • Loss of appetite
  • Soft, swollen spleen
  • Night sweats

The virus typically has an incubation period of four to eight weeks, although in young children this period may be shorter. Signs and symptoms such as fever and sore throat usually lessen within a couple of weeks, although fatigue, enlarged lymph nodes and a swollen spleen may last for a few weeks longer.

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