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In the latter stages of Chronic Obstructive Pulmonary Disease (COPD), complications can occur including diet and exercise-related problems such as weight loss, osteoporosis and muscle atrophy. Advanced cases can result in respiratory failure and oxygen depletion with excess carbon dioxide in the blood causing headaches or dizziness. As the heart works harder to pump blood, it can suffer serious damage resulting in pulmonary hypertension, heart disease or heart failure. The extremities may suffer from edema in ankle swelling.

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Q: What are the last signs before death of chronic obstructive pulmonary disease?
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