What are the major risks associated with pancreas transplantation surgery?

What are the risks of pancreas transplantation?

Diabetes and poor kidney function greatly increase the risk of complications from anesthesia during surgery. Organ rejection, excessive bleeding, and infection are other major risks associated with this surgery.

What risks are associated with Maze procedure?

The Maze procedure is major surgery and patients may experience any of the normal complications associated with major surgery and anesthesia, such as the risk of bleeding, pneumonia, or infection.

What are the causes of a new Kidney transplantation recipient to have a fever?

rejection is a possibility, or any other infection. But that is a major surgery, it wouldn't surprise me if fever is expected by the Dr's.

What is the main gastric bypass surgery risk?

There are indeed risks associated as this is major surgery. Patients can get heart attack or strokes if they are not monitored carefully after surgery.

What complications occur after hair transplantation?

Major complications as a result of hair transplantation are extremely rare

What risks are associated with hair transplantation?

Although there are rare cases of infection or scarring, the major risk is that the grafted area might not look the way the patient expected it to look.

What are the risks for limb salvage surgery?

The major risks associated with limb salvage are: superficial or deep infection at the site of the surgery; loosening, shifting, or breakage of implants;

What is the major source of lipase?

The major source of lipase in the body is the pancreas. Pancreatic lipase is an enzyme produced by the pancreas and plays a key role in breaking down fats in the small intestine during the digestion process.

What are major organs for digestion?

Liver, pancreas, intestines, stomach.

Pancreas transplant?

DefinitionA pancreas transplant is surgery to implant a healthy pancreas from a donor into a patient with diabetes. Pancreas transplants give the patient a chance to become independent of insulin injections.Alternative NamesTransplant - pancreas; Transplantation - pancreasDescriptionThe healthy pancreas is obtained from a donor who has suffered brain-death, but remains on life-support. The donor pancreas must meet numerous criteria to make sure it is suitable.A portion of the first part of the small intestine, called the duodenum, is transplanted along with the donor pancreas. The healthy pancreas is transported in a cooled solution that preserves the organ for up to 20 hours.The patient's diseased pancreas is not removed during the operation. The donor pancreas is usually placed in the right lower portion of the patient's abdomen. Blood vessels from the new pancreas are attachmented to the patient's blood vessels. The donor duodenum is attached to the patient's intestine or bladder to drain pancreatic secretions.The surgery for a pancreas transplant alone takes about 3 hours. However, the operation is usually done at the same time as a kidney transplantin diabetic patients with kidney disease. The combined operation takes about 6 hours.Why the Procedure Is PerformedThe pancreas makes a substance called insulin. Insulin moves glucose, which is sugar, from the blood into the muscles, fat, and liver cells, where it can be used as fuel. In people with type 1 diabetes, the pancreas doens't make enough, or sometimes any, insulin. This causes glucose to build up in the blood, resulting in high blood-sugar levels.A pancreas transplant can cure diabetes and eliminate the need for insulin shots. Because of the risks involved, however, most people with type 1 diabetes do not have a pancreas transplant soon after they are diagnosed.Pancreas transplant is major surgery, and people with diabetes have a high-than-normal risk of heart disease and other complications.People who've had a pancreas transplant will need to take several medicines for the rest of their lives. These medicines have serious side effects.Because of these risks, pancreas transplant is rarely done alone. It is almost always done when someone with type 1 diabetes also needs a kidney transplant.Pancreas transplant surgery may NOT be recommended for patients who also have:A history of cancerInfections such as hepatitis, which are considered to be activeLung diseaseMorbid obesityOther types of blood vessel diseases of the neck and legSevere heart disease (such as heart failure, poorly controlled angina, or severe coronary artery disease)Smoking, alcohol or drug abuse, or other lifestyle habits that can damage the new organThe doctor may also recommend against pancreas transplant if there is concern that the patient will not be able to comply with the many follow-up visits, tests, and medications needed to keep the transplanted organ healthy.RisksThe risks for any surgery are:BleedingBreathing problemsHeart attack or strokeInfection or abscessReactions to medicationsScar formationThe risks for pancreas transplant include:Blood clots (deep venous thrombosis)Clotting (thrombosis) of the arteries or veins of the new pancreasInflammation of the pancreas (pancreatitis)Leakage of fluid from the new pancrease where it attaches to the intestine or bladderThe body's immune system considers the transplanted organ foreign, and fights it accordingly. Thus, to prevent rejection, organ transplant patients must take drugs (such as cyclosporine and corticosteroids) that suppress (weaken) the body's immune response . This makes the person less able to fight various infections and can cause other medical problems.Before the ProcedurePatients undergoing pancreas transplant have chronic kidney disease along with their diabetes. Because of this, a very thorough evaluation for heart disease is done beforehand.See Kidney transplant.After the ProcedureSee Kidney transplant.Outlook (Prognosis)If the transplant is successful, you will no longer need to take insulin shots, test your blood-sugar daily, or follow a diabetic diet.There is evidence to suggest that the complications of diabetes, such as diabetic retinopathy, may not worsen -- and may even improve -- after a pancreas-kidney transplant.Drugs that prevent rejection of the donated pancreas and kidney must be taken for the rest of the patient's life.See Kidney transplant.ReferencesLipshutz GS, Wilkinson AH. Pancreas-kidney and pancreas transplantation for the treatment of diabetes mellitus. Endocrinol Metab Clin North Am. 2007;36(4).Markmann FJ, Yeh H, Naji A, et al. Transplantation of abdominal organs. In: Townsend CM, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2008: chap 28.

What is hypophysectomy's major risk?

A special risk associated with surgery on the pituitary is the risk of destroying the entire gland and leaving the entire endocrine system without regulation.

What risks are associated with salpingo-oophorectomy?

Major surgery always involves some risk, including infection, reactions to the anesthesia, hemorrhage, and scars at the incision site. Almost all pelvic surgery causes some internal scars, which, in some cases, can cause discomfort years after surgery.