answersLogoWhite

0

The mutations are in the Gs-alpha subunit ( for example, Arg485 to His) and leads to pseudohypoparathyroidism, also known as Albright Hereditary Osteodystrophy.

User Avatar

Wiki User

14y ago

What else can I help you with?

Related Questions

How do G protein-coupled receptors (GPCRs) interact with the G protein to initiate cellular signaling pathways?

When a signaling molecule binds to a G protein-coupled receptor (GPCR) on the cell surface, it causes a change in the receptor's shape. This change allows the GPCR to interact with a G protein inside the cell. The G protein then becomes activated and triggers a series of events that ultimately lead to the initiation of cellular signaling pathways.


How does a transmembrane receptor cause the stimulation of a cell does it take something from the chemokine and feed it through its transversile midsection and into the cell giving it to a transport?

N. Take a G protein linked receptor for an example. The ligand docks and causes a conformational change that causes a G protein to dock with the transmember protein receptor and initiate signal transduction through secondary messengers.


Is protein in sweetcorn?

3.2 g of protein in 100 g of sweetcorn.


What activates a G protein?

G protein is activated when a ligand (such as a hormone or neurotransmitter) binds to a G protein-coupled receptor (GPCR) on the cell membrane, causing a conformational change. This change allows GTP to bind to the G protein, replacing GDP, and activating the G protein to carry out downstream signaling cascades.


The toxin of Vibrio cholerae causes profuse diarrhea because it?

modifies a G protein involved in regulating salt and water secretion.


Why G protein linked receptor is called as G protein linked receptor?

sciece


Do all mutations result in malfunctioning proteins?

No (contrary to previous answer to this question) single base pair mutations, which swap out 1 base for another, say from an A to a G can be a "silent mutation" This means that the 3base "codon" that codes for an amino acid will still code for the same AA. AA's have about 3 different codons that will code for it, usually with the difference being in the last base pair. So for examples lets say AAC and AAT both code for Amino acid X, and the mutation causes the C in sequence AAC to change to a T it becomes AAT, and will still code for amino acid X.... no change in protein structure or function.


What has the author G Cazes written?

G. Cazes has written: 'Les mutations recentes de l'economie francaise'


What is gene g responsible for in these fruit flies?

Gene g in fruit flies is responsible for determining the color of their body. It codes for a specific protein that influences the pigmentation of the flies, resulting in variations in body color among individuals. Mutations in gene g can lead to changes in body color, which can be used to study gene expression and inheritance patterns.


What is Transducin?

A G protein


When was G protein-coupled receptors database created?

G protein-coupled receptors database was created in 1998.


What is bound to the G protein in the inactive state?

GDP. Guanine diphosphate. Then the protein is phosphorylated and undergoes a conformational change in concert with its docking with the G protein linked receptor.