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Maternal age influences the odds of conceiving a baby with Down syndrome.

The incidence of Down syndrome in a woman under 30 is approximately 1:1,000, according to the National Institutes for Health (NIH). This increases to approximately 1:400 by the age of 35, and to 1:12 by age 49.

Some breakdown figures from our contributors

At the maternal age of 20-24, the probability is 1:1562

At 37, the odds of having a child with Down syndrome are about 1:170 (according to my doctor from a top-ranked hospital as of Dec 2008).

At age 35-39, the probability is 1:214

Above age 45, the probability is 1:19.

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14y ago

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Related Questions

If you have a brother or a sister with Down syndrome does this increase the chances of giving birth to a child with Down syndrome?

Having a sibling with Down syndrome does not directly increase the chances of giving birth to a child with Down syndrome. The risk is influenced by maternal age, not family history. If both parents are carriers of the genetic translocation for Down syndrome, the risk may be higher.


How many cases have been recorded of a mother with Down syndrome giving birth to a normal baby?

The real answer can't really be known but this is a good article which discusses the subject somewhat. It is really rare that a woman with down syndrome gives birth ever because of the genetic problems, but it does happen. http://www.ncbi.nlm.nih.gov/pubmed/6211644


Is down syndrome caused by premature birth?

Down syndrome is not caused by premature birth. Down syndrome is present in the embryo from the time of conception. Down syndrome, in contrast, may lead to premature birth.


What are the chances that a mother with a Down syndrome child will have another child with Down syndrome if she gets pregnant at age 48?

A woman's risk of giving birth to a child with Down syndrome increases as she gets older. A 40 year old is much more likely to be in this situation than a 20 year old.


If you gave birth to two regular children - at age 32 and 35 - does that increase or decrease your risk of giving birth to a baby with Down syndrome now?

there are 6 kids in my family and everyone is completely normal


What age does down syndrome start to occur?

Down syndrome is something you are born with; it is not something that will suddenly "appear."


What age group is most affected by Down syndrome?

No age group is affected; Down syndrome is a chromosome condition that is with you at birth.


In which age bracket do people mostly get Down syndrome?

Down syndrome is something a baby has at birth. It is not a condition that you can "get" at a later age.


Is Down Syndrome a birth defect?

no it's not a birth defect...it's a disease caught way before birth..Down syndrome is when a person has 1 more chromosome than normal people.


How is it possible for two people with down syndrome to produce a normal healthy child?

no because since they both have down syndrome, they will have 100 percent that they will have a down syndrome baby


Can Down syndrome spread to other people?

No, Down syndrome is not contagious. It is a genetic/chromosomal difference - some may equate it to a birth defect, others to a birth enhancement


Does Down syndrome start at birth or does it develop as the persons ages?

Down syndrome is a genetic condition with which a person is born; it is not something that develops as the person gets older.