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Other than the possible side effect of the OTC meds separately you could get a possible overdose of acetaminophen.

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The problem is that acetaminophen (the generic name for "Tylenol") is one of the active ingredients in a LOT of other OTC and prescription medications. Including DayQuil, NyQuil, and many other "cold" remedies. Long term, repeatedly overdosing on acetaminophen can damage the liver, and liver failure is a NASTY way to die.

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Q: What are the reaction to Tylenol and dayquil togeher?
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