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There are four main subdivisions to the colon. The ascending colon, the transverse colon, the descending colon, and the sigmoid colon.

The ascending colon travels up the right side of the abdomen until it reaches the level of the right kidney. It then turns at a right angle (known as the right colic flexure) and travels across the abdominal cavity as the transverse colon. It then bends at a right angle again (known as the left colic flexure) and continues down the left side of the abdomen as the descending colon. The colon then enters the pelvis and becomes the 's' shaped sigmoid colon.

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