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a worsening of those found in chronic histoplasmosis, as well as weight loss, diarrhea, the development of open sores in the mouth and nose, and enlargement of the spleen, liver, and adrenal gland

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Q: What are the symptoms of disseminated histoplasmosis?
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What forms of histoplasmosis are potentially fatal?

Chronic histoplasmosis affects the lungs and can be fatal. Disseminated histoplasmosis affects many organ systems in the body and is often fatal


What are the symptoms of chronic histoplasmosis?

Symptoms of chronic histoplasmosis resemble those of tuberculosis. Cavities form in the lung tissue, parts of the lung may collapse, and the lungs fill with fluid


What is hystoplasmosis?

Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum. Its symptoms vary greatly, but the disease primarily affect the lungs.Histoplasmosis is an infectious disease caused by inhaling the microscopic spores of the fungus Histoplasma capsulatum. The disease exists in three forms. Acute or primary histoplasmosis causes flu-like symptoms. Most people who are infected recover without medical intervention. Chronic histoplasmosis affects the lungs and can be fatal. Disseminated histoplasmosis affects many organ systems in the body and is often fatal, especially to people with acquired immunodeficiency syndrome (AIDS).For the source and more detailed information concerning this subject, click on the related links section (Answers.com) indicated below.


What is a disseminated form of Histoplamosis?

One of three clinical forms of histoplasmosis. " (Severe) cases of histoplasmosis that fail to resolve and become chronic exhibiting pulmonary infiltration, cavitation, and fibrosis...particularly common in elderly patients and those exhibiting some form of immunosuppression." Cobb 1989


Histoplasmosis - disseminated?

DefinitionDisseminated histoplasmosis is a fungal infection that occurs after inhaling the spores of the fungus Histoplasma capsulatum.See also:HistoplasmosisHistoplasmosis - acuteHistoplasmosis - chronic pulmonarySkin lesion of histoplasmosisAlternative NamesSystemic histoplasmosisCauses, incidence, and risk factorsHistoplasmosis is caused by a fungus found in the central and eastern United States (Mississippi and Ohio River Valley), eastern Canada, Mexico, Central America, South America, Africa, and Southeast Asia.Most cases are mild or without symptoms. Acute pulmonary histoplasmosis may occur in epidemics after heavy exposure. Progressive or spreading (disseminated) and chronic disease can also occur. In disseminated disease, the infection has spread to other organs from the lungs through the bloodstream.The liver and spleen are usually enlarged, and any body organ may be involved. Ulcerations of the mouth or gastrointestinal tract may occur. Risk factors are travel to or residence within the central or eastern United States, and exposure to the droppings of birds and bats.SymptomsChillsCoughFeverHeadacheJoint painMental status changesMuscle aches and stiffnessNausea, vomitingPossible rash (erythema nodosum)Skin lesionsVisual changes (chorioretinitis)Signs and testsA physical examination may show abnormalities throughout the body.Tests used to diagnose disseminated histoplasmosis may include:Abdominal CT scanAbdominal ultrasoundBiopsy or culture of affected organs, bone marrow, liver, lymph node, lung, or skinBlood culturesChest x-rayComplete blood count (CBC)Histoplasma urinary antigen testMRI scan of the affected organsTreatmentDoctors prescribe antifungal medications to control the infection. Most patients should be treated for a year or more. Those who have suppressed immune systems (for example, from AIDS) may need lifelong treatment.Expectations (prognosis)The disease may progress rapidly and death can occur.ComplicationsMultiple organs are affected.Calling your health care providerCall your health care provider if you develop symptoms of disseminated histoplasmosis, particularly if you have been recently treated for acute or chronic histoplasmosis.Emergency symptoms include mental status changes and rapid worsening of the condition.PreventionAvoiding travel to areas where this spore is found can prevent the disease, but this may not be practical. Avoid bird or bat droppings if you are in one of these areas, especially if you are immunosuppressed.ReferencesKauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 353.


Is histoplasmosis a fungal disease?

Histoplasmosis is a fungal infection caused by inhaling spores of Histoplasma Capsulatum.


What are the symptoms of primary histoplasmosis?

The symptoms are usually mild and resemble those of a cold or flu; fever, dry cough, enlarged lymph glands, tiredness, and a general feeling of ill health. A small number of people develop bronchopneumonia.


What has the author T F Schlaegel written?

T. F. Schlaegel has written: 'Ocular histoplasmosis' -- subject(s): Eye Diseases, Histoplasmosis, Ocular histoplasmosis 'Essentials of uveitis' -- subject(s): Uveitis


Histoplasmosis - chronic pulmonary?

DefinitionChronic pulmonary histoplasmosis is a long-term respiratory infection caused by breathing the spores of the fungus, Histoplasma capsulatum.See also:Acute pulmonary histoplasmosisDisseminated histoplasmosisSkin lesion of histoplasmosisAlternative NamesChronic cavitary histoplasmosisCauses, incidence, and risk factorsHistoplasma capsulatum is a fungus found in the soil of the central and eastern United States (especially Mississippi and Ohio river valleys), eastern Canada, Mexico, Central America, and South America.The infection occurs when a person breathes in the reproducing parts of the fungus, called spores. Those who have a healthy immune system usually do not have symptoms, or only mild ones.This "acute" infection does not last, but can leave a person with small scars (granulomas). These scars can be difficult to distinguish from tumors in the lung.However, the infection can cause severe illness right away, or redevelop years after the first exposure, if a person's immune system is weakened by:CancerChemotherapyImmune-suppressing drugsHIV infectionRisk factors for chronic pulmonary histoplasmosis include:Living in or traveling to central or eastern United StatesExposure to soil or particles contaminated with droppings of chickens, bats, or blackbirdsPre-existing COPDWeakened immune system, such as in people who have AIDSSymptomsChillsCough that brings up blood, mucus, or pusFeverShortness of breathUnintentional weight lossSigns and testsTests that may be used to diagnose chronic pulmonary histoplasmosis include:Biopsy of infected tissue, such as open lung biopsyBronchoscopy with transbronchial biopsy or bronchoalveolar lavageCBCChest CT scanChest x-rayHistoplasma complement fixation titerHistoplasma urinary antigen test (positive only if the person also has disseminated histoplasmosis)Immunodiffusion testSputum cultureand stainTreatmentThe doctor will prescribe antifungal medications to control the infection within the lung. These medications must be taken for 1 to 2 years.Expectations (prognosis)The infection usually goes away with antifungal medication, but scarring inside the lung often remains. Histoplasmosis is unusual enough that if you develop it, your health care provider should check to find out whether another disease is weakening your immune system.Often, those who have had chronic pulmonary histoplasmosis must follow up with their doctor, who will check for signs of relapse.In rare cases, a pulmonary histoplasmosis infection can spread through the blood to other organs. This is called disseminated histoplasmosis. People who have a suppressed immune system and very young children are more likely to develop this condition. If this occurs, the prognosis is less favorable.ComplicationsArthritisDisseminated histoplasmosisLung scarring (fibrosis)PericarditisRespiratory insufficiencyPatients who breathe in a large amount of fungus can develop a severe and potentially deadly and sudden type of lung infection.Calling your health care providerCall for an appointment with your health care provider if you develop symptoms of chronic pulmonary histoplasmosis.Call your health care provider if your symptoms continue despite treatment, or if you have breathing difficulty or symptoms of disseminated histoplasmosis.PreventionBe aware of your surroundings, especially if you are in a weakened state from another medical condition, or from immune-suppressing medications.ReferencesKauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 353.What LJ, Freifeld AG, Kleiman MB, Baddley JW, McKinsey DS, Loyd JE, Kauffman CA. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis, 2007;45(7):807-825.


What is the treatment for chronic histoplasmosis?

Patients with an intact immune system who develop chronic histoplasmosis are treated with the drug ketoconazole (Nizoral) or amphotericin B (Fungizone).


Where is organization's annual report disseminated?

to whom is a report disseminated to and how is it done


Who discovered Histoplasmosis treatment?

Samuel Taylor darling