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Inflammation (Latin, inflammare, to set on fire) is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.[1] Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process. Inflammation is not a synonym for infection, even in cases where inflammation is caused by infection. Infection is caused by an exogenous pathogen, while inflammation is one of the responses of the organism to the pathogen.

Without inflammation, wounds and infections would never heal. Similarly, progressive destruction of the tissue would compromise the survival of the organism. However, chronic inflammation can also lead to a host of diseases, such as hay fever, atherosclerosis, and rheumatoid arthritis. It is for that reason that inflammation is normally closely regulated by the body.

Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes (especially granulocytes ) from the blood into the injured tissues. A cascade of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation and is characterized by simultaneous destruction and healing of the tissue from the (Source From Wikipedia)
Dolor- pain

Calor- heat

Rubor- erythema/redness

Tumor- swelling

Functio laesia- loss of function

the first 4 are attricutred to Celsus, some attribute the last to Galen.
The four signs and symptoms of inflammation are redness, pain, heat, and swelling. Inflammation can also cause the loss of function in the injured area, depending on the site and extent of the injury.
reness, swelling and pain in the area

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