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If you mean, "What are the 2 sub-categories the skeletal system is usually broken into?" the answer would be 'the axial and appendicular' sub-systems.

However, on the other hand, with the accent on the word "groups", you might include the vertebrae of the spine as one large, united group , despite that the system comprises many bones. As such it connects and supports the upper and lower extremities. Its arrangement also permits considerable flexibility and movement through the mid-section of the body.

It also acts as a protection and a channel for the conduct of the body's large nerves, which nerves effect action throughout the body and receive sensation and feedback to be recorded and recognized by the brain.

Other of the very large bones include those of the legs: the femur of the upper leg and the tibia and fibula of the lower. They are joined by the patella [knee bone] at the middle of the arrangement. These bones allow the whole body to stand upright and support it from otherwise merely lying on the ground (as in the snake, for instance).

They also act as levers over which the large muscles of the body act and give us movement over the surface of the earth.

White cells (which fight disease) are also produced in the skeletal system, generally.

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Q: What are the two large groups of bones within the skeletal system and what are their general functions?
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