The causes of CFIs include fighting and other forms of aggressive behavior, often combined with drug or alcohol consumption.
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Most CFIs result in tissue injury due to the force of impact, ragged-edged tears in the skin resulting from contact with the teeth, and contamination of the wound by the bacteria in human saliva.
CFIs can, however, have serious consequences, including infection, cellulitis, inflammation of the bone or bone marrow (osteomyelitis ), septic arthritis, and inflammation of the sheaths covering the tendons of the hand (tenosynovitis
Uninfected and relatively superficial CFIs may be treated with oral penicillin plus dicloxacillin or Augmentin. For infected CFIs, parenteral penicillin G is usually given together with nafcillin or cefuroxime.
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A clenched fist injury (CFI) is a bite wound on the hand, caused when a person's closed fist strikes the teeth of another person, usually in the course of a fight. CFIs are sometimes referred to as closed fist injuries or fight bites.
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