The major cause of Pickwickian syndrome is extreme obesity. This obesity places an excessive load on the pulmonary system. The role of genetics is also being studied
Pickwickian syndrome is entirely reversible if it is diagnosed and treated properly. If the problem goes undiagnosed, the outcome can be fatal.
Prevention of Pickwickian syndrome can be achieved by maintaining a healthy body weight and getting the proper amount of exercise.
Individuals with the Pickwickian syndrome are overweight, with large necks, fat buildup around the soft tissues of the neck, and loss of muscle tone with aging.
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The major health problem that occurs in patients with this disease is sleep apnea.
Deletion Mutation causes DiGeorges Syndrome.
is caused in part by the excess amounts of fatty tissue surrounding the chest muscles. This excess fat places a strain on the heart, lungs, and diaphragm of the patient, making it difficult to breathe.
The syndrome is named after a character in the Charles Dickens novel, The Pickwick Papers, who seemed to show some of the traits of this disease. Joe, a "fat red-faced boy," was always hungry, short of breath, and would fall asleep in the middle of performing tasks (narcolepsy from sleep apnea).
The cause of Behcet's syndrome is unknown
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Some tests that can be used to diagnose this condition include echocardiography to determine heart enlargement or pulmonary hypertension. Giving the patient multiple sleep latency tests can help give an objective measurement of daytime sleepiness.
ICE Syndrome