What causes pripism and its symptoms?

Answer 1

= Priapism Treatment = Check out the following sites for information on pripism, erectile dysfunction (ED), etc.

You possibly need to get medication, exercise, or contact your doctor or other healthcare provider. Causes The causative mechanisms are poorly understood but involve complex neurological and vascular factors. Priapism may be associated with prolonged sexual activity, leukaemia, Fabry's disease, haematological disorders (such as sickle-cell disease), cerebrospinal disease (such as syphilis), genital infection, some spinal injuries, or inflammation (Beers & Berkow, 1999). Priapism can be caused by drugs such as certain antidepressants, antihypertensives, anticoagulants and corticosteroids. It can also be a withdrawal symptom of drugs such as heroin. Priapism is often present in spinal injuries or trauma to the spinal cord.

One of the more significant classes of drugs which may precipitate priapism are the phosphodiesterase type-5 (PDE5) inhibitors such as sildenafil, tadalafil and vardenafil. Injected erectile-dysfunction therapies such as alprostadil are also significant. Complications Potential complications include ischaemia, clotting of the blood retained in the penis (thrombosis), and damage to the blood vessels of the penis which may result in an impaired erectile function or impotence. In serious cases the condition may result in gangrene, which may necessitate penis removal. Treatment Medical advice should be sought immediately for cases of priapism.

If the erection has been present for two hours the recommended therapy is pseudoephedrine 120 mg orally. If this has not subsided by four hours, a further 120 mg of pseudoephedrine is recommended. (Therapeutic Guidelines, 2001)

If the erection has been present for six hours, it is essential to contact a medical practitioner. The therapy at this stage is to aspirate blood from the corpus cavernosum under local anaesthetic. If this is still insufficient, then aspiration is conducted with injections of adrenaline as an adjuvant. (Therapeutic Guidelines, 2001)

If aspiration fails and tumescence re-occurs, surgical shunts are next attempted. These attempt to reverse the priapic state by shunting blood from the rigid corpora cavernosa into the corpus spongiosum (which contains the glans and the urethra). Distal shunts are the first step, followed by more proximal shunts.

Should all else fail, complete removal of the penis is necessary. = Priapism Treatment = Check out the following sites for information on pripism, erectile dysfunction (ED), etc.

You possibly need to get medication, exercise, or contact your doctor or other healthcare provider. Causes The causative mechanisms are poorly understood but involve complex neurological and vascular factors. Priapism may be associated with prolonged sexual activity, leukaemia, Fabry's disease, haematological disorders (such as sickle-cell disease), cerebrospinal disease (such as syphilis), genital infection, some spinal injuries, or inflammation (Beers & Berkow, 1999). Priapism can be caused by drugs such as certain antidepressants, antihypertensives, anticoagulants and corticosteroids. It can also be a withdrawal symptom of drugs such as heroin. Priapism is often present in spinal injuries or trauma to the spinal cord.

One of the more significant classes of drugs which may precipitate priapism are the phosphodiesterase type-5 (PDE5) inhibitors such as sildenafil, tadalafil and vardenafil. Injected erectile-dysfunction therapies such as alprostadil are also significant. Complications Potential complications include ischaemia, clotting of the blood retained in the penis (thrombosis), and damage to the blood vessels of the penis which may result in an impaired erectile function or impotence. In serious cases the condition may result in gangrene, which may necessitate penis removal. Treatment Medical advice should be sought immediately for cases of priapism.

If the erection has been present for two hours the recommended therapy is pseudoephedrine 120 mg orally. If this has not subsided by four hours, a further 120 mg of pseudoephedrine is recommended. (Therapeutic Guidelines, 2001)

If the erection has been present for six hours, it is essential to contact a medical practitioner. The therapy at this stage is to aspirate blood from the corpus cavernosum under local anaesthetic. If this is still insufficient, then aspiration is conducted with injections of adrenaline as an adjuvant. (Therapeutic Guidelines, 2001)

If aspiration fails and tumescence re-occurs, surgical shunts are next attempted. These attempt to reverse the priapic state by shunting blood from the rigid corpora cavernosa into the corpus spongiosum (which contains the glans and the urethra). Distal shunts are the first step, followed by more proximal shunts.

Should all else fail, complete removal of the penis is necessary.